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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_032977.2 RefSeqGene
- Range
-
5523..96374
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_707
mRNA and Protein(s)
-
NM_001258214.1 → NP_001245143.1 interleukin-12 receptor subunit beta-2 isoform b precursor
See identical proteins and their annotated locations for NP_001245143.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate coding exon compared to variant 1, that causes a frameshift. Variants 2 and 7 encode the same isoform (b), which has a shorter and distinct C-terminus, compared to isoform a.
- Source sequence(s)
-
AK294494, AL358512, AL389925, DA223630, DB126833, U64198
- Consensus CDS
-
CCDS58006.1
- UniProtKB/TrEMBL
- B4DGA4, B7ZB60
- Related
- ENSP00000360039.1, ENST00000371000.5
- Conserved Domains (3) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
- cl21522
Location:127 → 179
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_001258215.1 → NP_001245144.1 interleukin-12 receptor subunit beta-2 isoform c precursor
See identical proteins and their annotated locations for NP_001245144.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
- Source sequence(s)
-
AL358512, AL389925, BC143249, DB126833, U64198
- Consensus CDS
-
CCDS58007.1
- UniProtKB/Swiss-Prot
-
Q99665
- Related
- ENSP00000442443.1, ENST00000544434.5
- Conserved Domains (3) summary
-
- cd00063
Location:423 → 529
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
- cl21522
Location:127 → 179
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_001258216.1 → NP_001245145.1 interleukin-12 receptor subunit beta-2 isoform d precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks two alternate coding exons compared to variant 1, that causes a frameshift. The resulting isoform (d) has a shorter and distinct C-terminus compared to isoform a.
- Source sequence(s)
-
AL358512, AL389925, BC143250, DB126833, U64198
- Consensus CDS
-
CCDS72805.1
- UniProtKB/TrEMBL
- A0A8Q3SIS8, A0A8Q3SIX0
- Related
- ENSP00000512853.1, ENST00000696755.1
- Conserved Domains (3) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
- cl21522
Location:127 → 179
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_001319233.1 → NP_001306162.1 interleukin-12 receptor subunit beta-2 isoform b precursor
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) differs in the 5' UTR and lacks an alternate exon in the 3' coding region, resulting in a frameshift and an early stop codon, compared to variant 1. Variants 2 and 7 encode the same isoform (b), which has a shorter and distinct C-terminus, compared to isoform a.
- Source sequence(s)
-
AK294494, AK316525, AL358512, AL389925, BC143248, U64198
- Consensus CDS
-
CCDS58006.1
- UniProtKB/TrEMBL
- B4DGA4, B7ZB60
- Conserved Domains (3) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
- cl21522
Location:127 → 179
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
NM_001374259.2 → NP_001361188.1 interleukin-12 receptor subunit beta-2 isoform a precursor
Status: REVIEWED
- Source sequence(s)
-
AL358512, AL389925
- Consensus CDS
-
CCDS638.1
- UniProtKB/Swiss-Prot
- B1AN98, B7ZKL9, F5H7L6, Q2M3V3, Q99665
- Related
- ENSP00000501329.1, ENST00000674203.2
- Conserved Domains (2) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
-
NM_001559.3 → NP_001550.1 interleukin-12 receptor subunit beta-2 isoform a precursor
See identical proteins and their annotated locations for NP_001550.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (a).
- Source sequence(s)
-
AL358512, AL389925
- Consensus CDS
-
CCDS638.1
- UniProtKB/Swiss-Prot
- B1AN98, B7ZKL9, F5H7L6, Q2M3V3, Q99665
- Related
- ENSP00000262345.1, ENST00000262345.5
- Conserved Domains (2) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
RNA
-
NR_047583.1 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks an alternate in-frame exon and lacks another alternate coding exon compared to variant 1, that causes a frameshift. The resulting transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is therefore thought to be non-protein coding.
- Source sequence(s)
-
AL358512, AL389925, BC143248, DB126833, U64198
-
NR_047584.1 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) contains an alternate exon compared to variant 1, that causes a frameshift. The resulting transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is therefore thought to be non-protein coding.
- Source sequence(s)
-
AL358512, AL389925, BC143252, DB126833, U64198
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
67307364..67398724
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011541384.3 → XP_011539686.1 interleukin-12 receptor subunit beta-2 isoform X2
- Conserved Domains (3) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
- cl21522
Location:127 → 179
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
XM_006710617.3 → XP_006710680.1 interleukin-12 receptor subunit beta-2 isoform X3
See identical proteins and their annotated locations for XP_006710680.1
- UniProtKB/Swiss-Prot
-
Q99665
- Conserved Domains (3) summary
-
- cd00063
Location:423 → 529
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
- cl21522
Location:127 → 179
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
XM_005270827.3 → XP_005270884.1 interleukin-12 receptor subunit beta-2 isoform X1
See identical proteins and their annotated locations for XP_005270884.1
- UniProtKB/Swiss-Prot
- B1AN98, B7ZKL9, F5H7L6, Q2M3V3, Q99665
- Related
- ENSP00000497959.1, ENST00000648487.1
- Conserved Domains (2) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
-
XM_017001203.2 → XP_016856692.1 interleukin-12 receptor subunit beta-2 isoform X4
- UniProtKB/TrEMBL
- B4DGA4, B7ZB60
- Related
- ENSP00000512854.1, ENST00000696757.1
- Conserved Domains (3) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
- cl21522
Location:127 → 179
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
-
XM_047419665.1 → XP_047275621.1 interleukin-12 receptor subunit beta-2 isoform X2
-
XM_047419669.1 → XP_047275625.1 interleukin-12 receptor subunit beta-2 isoform X5
- UniProtKB/TrEMBL
-
A0A0A0MTN7
- Related
- ENSP00000445276.3, ENST00000541374.6
-
XM_005270828.4 → XP_005270885.1 interleukin-12 receptor subunit beta-2 isoform X1
See identical proteins and their annotated locations for XP_005270885.1
- UniProtKB/Swiss-Prot
- B1AN98, B7ZKL9, F5H7L6, Q2M3V3, Q99665
- Conserved Domains (2) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
-
XM_047419668.1 → XP_047275624.1 interleukin-12 receptor subunit beta-2 isoform X4
- UniProtKB/TrEMBL
- B4DGA4, B7ZB60
-
XM_047419666.1 → XP_047275622.1 interleukin-12 receptor subunit beta-2 isoform X2
-
XM_047419667.1 → XP_047275623.1 interleukin-12 receptor subunit beta-2 isoform X3
-
XM_011541383.3 → XP_011539685.1 interleukin-12 receptor subunit beta-2 isoform X1
See identical proteins and their annotated locations for XP_011539685.1
- UniProtKB/Swiss-Prot
- B1AN98, B7ZKL9, F5H7L6, Q2M3V3, Q99665
- Conserved Domains (2) summary
-
- cd00063
Location:423 → 511
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam06328
Location:28 → 110
- Lep_receptor_Ig; Ig-like C2-type domain
-
XM_047419670.1 → XP_047275626.1 interleukin-12 receptor subunit beta-2 isoform X6
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
67181083..67276270
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054336407.1 → XP_054192382.1 interleukin-12 receptor subunit beta-2 isoform X1
- UniProtKB/Swiss-Prot
- B1AN98, B7ZKL9, F5H7L6, Q2M3V3, Q99665
-
XM_054336408.1 → XP_054192383.1 interleukin-12 receptor subunit beta-2 isoform X1
- UniProtKB/Swiss-Prot
- B1AN98, B7ZKL9, F5H7L6, Q2M3V3, Q99665
-
XM_054336410.1 → XP_054192385.1 interleukin-12 receptor subunit beta-2 isoform X2
-
XM_054336409.1 → XP_054192384.1 interleukin-12 receptor subunit beta-2 isoform X1
- UniProtKB/Swiss-Prot
- B1AN98, B7ZKL9, F5H7L6, Q2M3V3, Q99665
-
XM_054336411.1 → XP_054192386.1 interleukin-12 receptor subunit beta-2 isoform X6