Vmn2r115 vomeronasal 2, receptor 115 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Vmn2r115provided by MGI
Official Full Name: vomeronasal 2, receptor 115provided by MGI
Primary source: MGI:MGI:3647235
See related: Ensembl:ENSMUSG00000091076 AllianceGenome:MGI:3647235
Gene type: protein coding
RefSeq status: INFERRED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: V2Rp4; EG638102
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 17 A3.3; 17 11.56 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (23562951..23579102)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (23343977..23360128)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Exocrine gland-secreting peptide 22 (ESP22) activates vomeronasal receptor, V2Rp4, and V2Rp4 knockout eliminates ESP22 effects on sexual behavior. V2Rp4 counteracts a highly related vomeronasal receptor, V2Rp5, that detects the male sex pheromone ESP1.
Title: Sexual rejection via a vomeronasal receptor-triggered limbic circuit.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2) 1 citation

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: vomeronasal receptor Vmn2r115

Names: vomeronasal 2 receptor p4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001104579.1 → NP_001098049.1 vomeronasal receptor Vmn2r115 precursor

See identical proteins and their annotated locations for NP_001098049.1

Status: INFERRED

Source sequence(s)

CT485617

Consensus CDS

CCDS50008.1

UniProtKB/TrEMBL

D7URW4, E9PW45, E9PYG3, E9Q0E7, E9Q7B2

Related

ENSMUSP00000131447.2, ENSMUST00000168175.3

Conserved Domains (4) summary

cd06365
Location:41 → 504

PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

pfam00003
Location:599 → 832

7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR

pfam01094
Location:75 → 471

ANF_receptor; Receptor family ligand binding region

pfam07562
Location:513 → 564

NCD3G; Nine Cysteines Domain of family 3 GPCR