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    aslB putative anaerobic sulfatase maturation enzyme AslB [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 949013, updated on 3-Dec-2024

    Summary

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    Official Symbol
    aslB
    Official Full Name
    putative anaerobic sulfatase maturation enzyme AslB
    Primary source
    ECOCYC:EG10090
    Locus tag
    b3800
    See related
    ASAP:ABE-0012408
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    atsB; ECK3793; gppB
    Summary
    Radical SAM superfamily. [More information is available at EcoGene: EG10090]. AslB is a member of the anaerobic sulfatase maturation enzyme subfamily of the Radical SAM superfamily of enzymes . [More information is available at EcoCyc: EG10090].
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    Genomic context

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    Sequence:
    NC_000913.3 (3982958..3984193)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene tRNA-Pro Neighboring gene putative sulfatase AslA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Anaerobic sulfatase maturase AslB from Escherichia coli activates human recombinant iduronate-2-sulfate sulfatase (IDS) and N-acetylgalactosamine-6-sulfate sulfatase (GALNS). Alméciga-Díaz CJ, et al. Gene, 2017 Nov 15. PMID 28882567
    2. Spacing mutations between the Escherichia coli pBAD RNA polymerase binding site and the araC (I) induction site. Hendrickson W, et al. Nucleic Acids Res, 1983 Mar 25. PMID 6300782, Free PMC Article
    3. A novel mucin-sulphatase activity found in Burkholderia cepacia and Pseudomonas aeruginosa. Jansen HJ, et al. J Med Microbiol, 1999 Jun. PMID 10359304
    4. Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility. Hanson SR, et al. Angew Chem Int Ed Engl, 2004 Nov 5. PMID 15493058
    5. First evidences for a third sulfatase maturation system in prokaryotes from E. coli aslB and ydeM deletion mutants. Benjdia A, et al. FEBS Lett, 2007 Mar 6. PMID 17303125

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cys-type sulfatases can mature only in aerobic conditions, and knocking-out of aslB, ydeM and yidF does not impair Cys-type sulfatase maturation.
      Title: First evidences for a third sulfatase maturation system in prokaryotes from E. coli aslB and ydeM deletion mutants.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein maturation ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    acts_upstream_of_or_within protein maturation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative anaerobic sulfatase maturation enzyme AslB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3982958..3984193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026259.1 putative anaerobic sulfatase maturation enzyme AslB [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026259.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8S7EIE1
      Conserved Domains (1) summary
      TIGR03942
      Location:11 → 391
      sulfatase_rSAM; anaerobic sulfatase-maturating enzyme
    Nucleotide Protein
    Heading Accession and Version

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