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    yeeO FMN/FAD exporter [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946506, updated on 17-Dec-2024

    Summary

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    Official Symbol
    yeeO
    Official Full Name
    FMN/FAD exporter
    Primary source
    ECOCYC:G7070
    Locus tag
    b1985
    See related
    ASAP:ABE-0006586
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1980
    Summary
    Multi Antimicrobial Extrusion (MATE) family member, PF01554 and IPR002528. [More information is available at EcoGene: EG13383]. The YeeO protein is an uncharacterised member of the MATE family of multidrug efflux transporters . [More information is available at EcoCyc: G7070].
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    Genomic context

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    Sequence:
    NC_000913.3 (2058203..2059846, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transcriptional regulator YeeN Neighboring gene tRNA-Asn Neighboring gene tRNA-Asn Neighboring gene DNA-binding transcriptional activator Cbl

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. NorM, a putative multidrug efflux protein, of Vibrio parahaemolyticus and its homolog in Escherichia coli. Morita Y, et al. Antimicrob Agents Chemother, 1998 Jul. PMID 9661020, Free PMC Article
    2. YeeO from Escherichia coli exports flavins. McAnulty MJ, et al. Bioengineered, 2014. PMID 25482085, Free PMC Article
    3. The multidrug efflux protein NorM is a prototype of a new family of transporters. Brown MH, et al. Mol Microbiol, 1999 Jan. PMID 9987140
    4. Sequences that direct significant levels of frameshifting are frequent in coding regions of Escherichia coli. Gurvich OL, et al. EMBO J, 2003 Nov 3. PMID 14592990, Free PMC Article
    5. Effect of multidrug-efflux transporter genes on dipeptide resistance and overproduction in Escherichia coli. Hayashi M, et al. FEMS Microbiol Lett, 2010 Mar. PMID 20067529

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables FAD transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables FMN transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dipeptide transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables xenobiotic transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within FAD transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in carbohydrate derivative transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within dipeptide transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in peptide transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in xenobiotic transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    FMN/FAD exporter

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2058203..2059846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416491.3 FMN/FAD exporter [Escherichia coli str. K-12 substr. MG1655]

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3H9EMP1, A0A3P1GEY8, A0A4V4SX43, A0A5N3CVL9, A0A8S7EK43, A0A8S7R271, A0A9Q6Y2Z8, A0AAD2NUW1, A0AAE4XDV0, A0AAN2SBV2, A0AAN3Q8S0, A0AAQ2I8A0
      Conserved Domains (1) summary
      PRK10189
      Location:64 → 541
      PRK10189; EmmdR/YeeO family multidrug/toxin efflux MATE transporter
    Nucleotide Protein
    Heading Accession and Version

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