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    gltP glutamate/aspartate : H(+) symporter GltP [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948591, updated on 3-Dec-2024

    Summary

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    Official Symbol
    gltP
    Official Full Name
    glutamate/aspartate : H(+) symporter GltP
    Primary source
    ECOCYC:EG10405
    Locus tag
    b4077
    See related
    ASAP:ABE-0013357
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4070
    Summary
    Escherichia coli contains four transporters for the uptake of glutamate (GltIJKL, GltP, GltS, and GadC) and five transporters for the uptake of aspartate (GltIJKL, GltP, DctA, DcuA, and DcuB). [More information is available at EcoCyc: EG10405].
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    Genomic context

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    Sequence:
    NC_000913.3 (4294481..4295794)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative cytochrome c-type biogenesis protein NrfE Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfF Neighboring gene putative formate-dependent nitrite reductase complex subunit NrfG Neighboring gene Sel1 repeat-containing protein YjcO Neighboring gene formate dehydrogenase H

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Revised nucleotide sequence of the gltP gene, which encodes the proton-glutamate-aspartate transport protein of Escherichia coli K-12. Tolner B, et al. J Bacteriol, 1992 Apr. PMID 1551855, Free PMC Article
    2. Cloning and sequencing of a gene encoding a glutamate and aspartate carrier of Escherichia coli K-12. Wallace B, et al. J Bacteriol, 1990 Jun. PMID 1971622, Free PMC Article
    3. Calcium channel subtypes in rat brain: biochemical characterization of the high-affinity receptors for omega-conopeptides SNX-230 (synthetic MVIIC), SNX-183 (SVIB), and SNX-111 (MVIIA). Woppmann A, et al. Mol Cell Neurosci, 1994 Aug. PMID 7804605
    4. Location of the gltP gene on the physical map of Escherichia coli K-12. Lum D, et al. J Bacteriol, 1993 Sep. PMID 8366064, Free PMC Article
    5. Structure and function of prokaryotic glutamate transporters from Escherichia coli and Pyrococcus horikoshii. Raunser S, et al. Biochemistry, 2006 Oct 24. PMID 17042498

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables amino acid:proton symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in carboxylic acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in dicarboxylic acid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in dicarboxylic acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within dicarboxylic acid transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glutamate/aspartate : H(+) symporter GltP

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4294481..4295794
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418501.1 glutamate/aspartate : H(+) symporter GltP [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418501.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2H4TRW6, A0A376VTQ6, A0A5B9AM23
      Conserved Domains (1) summary
      PRK11283
      Location:1 → 437
      gltP; glutamate/aspartate:proton symporter; Provisional
    Nucleotide Protein
    Heading Accession and Version

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