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    ecnA entericidin A lipoprotein, antidote to entericidin B [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 2847736, updated on 17-Dec-2024

    Summary

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    Official Symbol
    ecnA
    Official Full Name
    entericidin A lipoprotein, antidote to entericidin B
    Primary source
    ECOCYC:G0-41
    Locus tag
    b4410
    See related
    ASAP:ABE-0047210
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4142
    Summary
    First 18 aa are a type II signal peptide. [More information is available at EcoGene: EG14372]. EcnAB form a linked toxin-antitoxin "addiction module" which functions to regulate programmed bacterial cell death under high osmolarity conditions. [More information is available at EcoCyc: G0-41].
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    Genomic context

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    Sequence:
    NC_000913.3 (4376317..4376442)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene lysine 2,3-aminomutase Neighboring gene protein chain elongation factor EF-P Neighboring gene bacteriolytic entericidin B lipoprotein Neighboring gene guanidinium exporter Neighboring gene outer membrane lipoprotein Blc

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Juncker AS, et al. Protein Sci, 2003 Aug. PMID 12876315, Free PMC Article
    2. Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Gonnet P, et al. Proteomics, 2004 Jun. PMID 15174130
    3. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article
    4. The entericidin locus of Escherichia coli and its implications for programmed bacterial cell death. Bishop RE, et al. J Mol Biol, 1998 Jul 24. PMID 9677290
    5. Small membrane proteins found by comparative genomics and ribosome binding site models. Hemm MR, et al. Mol Microbiol, 2008 Dec. PMID 19121005, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    involved_in response to toxic substance IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    entericidin A lipoprotein, antidote to entericidin B

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4376317..4376442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_026283.1 entericidin A lipoprotein, antidote to entericidin B [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for YP_026283.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A0H3ESD0, A0A1X3J6S7, A0A3L9IBA8, A0AAJ3NY58, F4T7U9
      Conserved Domains (1) summary
      PRK09810
      Location:1 → 41
      PRK09810; lipoprotein antitoxin entericidin A
    Nucleotide Protein
    Heading Accession and Version

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