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    gyrB DNA gyrase subunit B [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879230, updated on 24-Aug-2024

    Summary

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    Gene symbol
    gyrB
    Gene description
    DNA gyrase subunit B
    Locus tag
    PA0004
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (4275..6695)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene chromosome replication initiator DnaA Neighboring gene DNA polymerase III subunit beta Neighboring gene DNA replication and repair protein RecF Neighboring gene lysophosphatidic acid acyltransferase Neighboring gene D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The bacteriophage LUZ24 "Igy" peptide inhibits the Pseudomonas DNA gyrase. De Smet J, et al. Cell Rep, 2021 Aug 24. PMID 34433028
    2. Hydrolysis of ATP at only one GyrB subunit is sufficient to promote supercoiling by DNA gyrase. Kampranis SC, et al. J Biol Chem, 1998 Oct 9. PMID 9756859
    3. DNA supercoiling in gyrase mutants. Steck TR, et al. J Bacteriol, 1984 May. PMID 6327603, Free PMC Article
    4. The binding of gyrase to DNA: analysis by retention by nitrocellulose filters. Higgins NP, et al. Nucleic Acids Res, 1982 Nov 11. PMID 6294616, Free PMC Article
    5. Energy coupling in DNA gyrase and the mechanism of action of novobiocin. Sugino A, et al. Proc Natl Acad Sci U S A, 1978 Oct. PMID 368801, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The bacteriophage LUZ24 ""Igy"" peptide inhibits the Pseudomonas DNA gyrase.
      Title: The bacteriophage LUZ24 "Igy" peptide inhibits the Pseudomonas DNA gyrase.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA topological change ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA gyrase subunit B
    NP_064724.1
    • Product name confidence: class 2 (High similarity to functionally studied protein)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      4275..6695
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_064724.1 DNA gyrase subunit B [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_064724.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9S1C7
      Conserved Domains (1) summary
      PRK14939
      Location:1 → 806
      gyrB; DNA gyrase subunit B; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9I7C2.1

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