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    fabB 3-oxoacyl-ACP synthase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 881925, updated on 24-Aug-2024

    Summary

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    Gene symbol
    fabB
    Gene description
    3-oxoacyl-ACP synthase
    Locus tag
    PA1609
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (1751674..1752891, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene chemotaxis transducer Neighboring gene 3-hydroxydecanoyl-ACP dehydratase Neighboring gene sensor/response regulator hybrid protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of molecular mechanisms controlling fabAB transcription in Pseudomonas aeruginosa. Schweizer HP, et al. PLoS One, 2012. PMID 23056212, Free PMC Article
    2. Structural, enzymatic, and genetic studies of beta-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli. Garwin JL, et al. J Biol Chem, 1980 Dec 25. PMID 7002930
    3. Fatty acid biosynthesis in Pseudomonas aeruginosa: cloning and characterization of the fabAB operon encoding beta-hydroxyacyl-acyl carrier protein dehydratase (FabA) and beta-ketoacyl-acyl carrier protein synthase I (FabB). Hoang TT, et al. J Bacteriol, 1997 Sep. PMID 9286984, Free PMC Article
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data suggest a promoter requiring an activator for RNA polymerase binding to initiate fabAB transcription.
      Title: Characterization of molecular mechanisms controlling fabAB transcription in Pseudomonas aeruginosa.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables 3-oxoacyl-[acyl-carrier-protein] synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within unsaturated fatty acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-oxoacyl-ACP synthase
    NP_250300.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1751674..1752891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250300.1 3-oxoacyl-ACP synthase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250300.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      O33878
      Conserved Domains (1) summary
      PRK07967
      Location:1 → 405
      PRK07967; beta-ketoacyl-ACP synthase I
    Nucleotide Protein
    Heading Accession and Version

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