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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_009784.1 RefSeqGene
- Range
-
5068..17841
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001081560.3 → NP_001075029.1 myotonin-protein kinase isoform 3
See identical proteins and their annotated locations for NP_001075029.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has multiple differences in the presence and absence of exons at its 5' end and in the CDS, compared to variant 1. These differences produce a distinct 5' UTR, cause translation initiation at an alternative start codon, and the loss of an in-frame portion of the coding region, compared to variant 1. The encoded protein (isoform 3, also known as isoform 11) has a distinct N-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AC011530, AV655848, BC062553, L19268
- Consensus CDS
-
CCDS46118.1
- UniProtKB/TrEMBL
- B4DZE2, E5KR07
- Related
- ENSP00000413417.1, ENST00000447742.6
- Conserved Domains (2) summary
-
- pfam08826
Location:465 → 525
- DMPK_coil; DMPK coiled coil domain like
- cd05597
Location:69 → 401
- STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
-
NM_001081562.3 → NP_001075031.1 myotonin-protein kinase isoform 4
See identical proteins and their annotated locations for NP_001075031.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) has multiple differences in the presence and absence of exons at its 5' end and in the CDS, compared to variant 1. These differences produce a distinct 5' UTR, and cause translation initiation at an alternative start codon, the loss of an in-frame portion of the coding region and a frameshift in the 3' coding region, compared to variant 1. The encoded protein (isoform 4) has a distinct N-terminus and a unique C-terminus, and is shorter than isoform 1.
- Source sequence(s)
-
AC011530, AV655848, BC062553, S72883
- Consensus CDS
-
CCDS46117.1
- UniProtKB/TrEMBL
- B4DM55, E5KR05
- Related
- ENSP00000401753.1, ENST00000458663.6
- Conserved Domains (2) summary
-
- pfam08826
Location:465 → 525
- DMPK_coil; DMPK coiled coil domain like
- cd05597
Location:69 → 401
- STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
-
NM_001081563.3 → NP_001075032.1 myotonin-protein kinase isoform 1
See identical proteins and their annotated locations for NP_001075032.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1), also known as Form I.
- Source sequence(s)
-
AC011530, AC074212
- UniProtKB/TrEMBL
-
X5DNJ6
- Conserved Domains (3) summary
-
- pfam08826
Location:480 → 540
- DMPK_coil; DMPK coiled coil domain like
- smart00220
Location:81 → 349
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd05597
Location:79 → 416
- STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
-
NM_001288764.2 → NP_001275693.1 myotonin-protein kinase isoform 5
See identical proteins and their annotated locations for NP_001275693.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) has multiple differences in the presence and absence of exons at its 5' end, compared to variant 1. These differences produce a distinct 5' UTR, and cause translation initiation at an alternative start codon, compared to variant 1. The encoded protein (isoform 5) has a distinct N-terminus and is longer than isoform 1.
- Source sequence(s)
-
AC011530, AC074212, BC026328
- UniProtKB/TrEMBL
-
I6L989
- Conserved Domains (3) summary
-
- pfam08826
Location:496 → 556
- DMPK_coil; DMPK coiled coil domain like
- smart00220
Location:97 → 365
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cd05597
Location:95 → 432
- STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
-
NM_001288765.2 → NP_001275694.1 myotonin-protein kinase isoform 6
See identical proteins and their annotated locations for NP_001275694.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) has multiple differences in the presence and absence of exons at its 5' end, compared to variant 1. These differences produce a distinct 5' UTR, and cause translation initiation at an alternative start codon, compared to variant 1. The encoded protein (isoform 6) has a shorter and distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AC011530, AK297299, BC026328, BG152972, DC420602, M94203
- UniProtKB/TrEMBL
-
B4DM55
- Related
-
ENST00000596686.5
- Conserved Domains (3) summary
-
- pfam08826
Location:381 → 441
- DMPK_coil; DMPK coiled coil domain like
- smart00220
Location:2 → 250
- S_TKc; Serine/Threonine protein kinases, catalytic domain
- cl21453
Location:1 → 317
- PKc_like; Protein Kinases, catalytic domain
-
NM_001288766.2 → NP_001275695.1 myotonin-protein kinase isoform 7
See identical proteins and their annotated locations for NP_001275695.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) has multiple differences in the presence and absence of exons at its 5' end, compared to variant 1. These differences produce a distinct 5' UTR, cause translation initiation at an alternative start codon, loss of an in-frame portion of the 3' coding region, and a frameshift in the 3' coding region, compared to variant 1. The encoded protein (isoform 7) has a distinct C-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AC074212, AK302874, BC026328, BP422066, BQ670576, HY031977
- Consensus CDS
-
CCDS74400.1
- UniProtKB/TrEMBL
-
B4DZE2
- Related
- ENSP00000346168.5, ENST00000354227.9
- Conserved Domains (2) summary
-
- pfam08826
Location:465 → 525
- DMPK_coil; DMPK coiled coil domain like
- cd05597
Location:69 → 401
- STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
-
NM_001424159.1 → NP_001411088.1 myotonin-protein kinase isoform 2
Status: REVIEWED
- Source sequence(s)
-
CP068259
- UniProtKB/Swiss-Prot
- E5KR08, Q09013, Q16205, Q6P5Z6
- UniProtKB/TrEMBL
- B4DZE2, E5KR06
-
NM_001424160.1 → NP_001411089.1 myotonin-protein kinase isoform 8
Status: REVIEWED
- Source sequence(s)
-
CP068259
- UniProtKB/TrEMBL
-
B4DZE2
-
NM_001424161.1 → NP_001411090.1 myotonin-protein kinase isoform 7
Status: REVIEWED
- Source sequence(s)
-
CP068259
- UniProtKB/TrEMBL
-
B4DZE2
-
NM_001424162.1 → NP_001411091.1 myotonin-protein kinase isoform 14
Status: REVIEWED
- Source sequence(s)
-
AC011530, AC074212
- UniProtKB/TrEMBL
-
B4DM55
- Related
- ENSP00000345997.4, ENST00000343373.10
-
NM_001424163.1 → NP_001411092.1 myotonin-protein kinase isoform 10
Status: REVIEWED
- Source sequence(s)
-
AC011530, AC074212
- UniProtKB/TrEMBL
-
B4DM55
-
NM_001424164.1 → NP_001411093.1 myotonin-protein kinase isoform 8
Status: REVIEWED
- Source sequence(s)
-
AC011530, AC074212
- UniProtKB/TrEMBL
-
B4DZE2
- Related
- ENSP00000508381.1, ENST00000683086.1
-
NM_001424165.1 → NP_001411094.1 myotonin-protein kinase isoform 11
Status: REVIEWED
- Source sequence(s)
-
AC011530, AC074212
- UniProtKB/TrEMBL
-
B4DZE2
-
NM_001424166.1 → NP_001411095.1 myotonin-protein kinase isoform 12
Status: REVIEWED
- Source sequence(s)
-
AC011530, AC074212
- UniProtKB/TrEMBL
-
B4DM55
-
NM_001424168.1 → NP_001411097.1 myotonin-protein kinase isoform 15
Status: REVIEWED
- Source sequence(s)
-
AC011530, AC074212
- UniProtKB/TrEMBL
-
B4DZE2
-
NM_001424169.1 → NP_001411098.1 myotonin-protein kinase isoform 13
Status: REVIEWED
- Source sequence(s)
-
AC011530, AC074212
- UniProtKB/TrEMBL
-
B4DZE2
-
NM_004409.5 → NP_004400.4 myotonin-protein kinase isoform 2
See identical proteins and their annotated locations for NP_004400.4
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has multiple differences in the presence and absence of exons at its 5' end, compared to variant 1. These differences produce a distinct 5' UTR and cause translation initiation at an alternative start codon, compared to variant 1. The encoded protein (isoform 2, also known as isoform 9) has a distinct N-terminus and is shorter than isoform 1.
- Source sequence(s)
-
AV655848, BC062553, BG706056
- Consensus CDS
-
CCDS12674.1
- UniProtKB/Swiss-Prot
- E5KR08, Q09013, Q16205, Q6P5Z6
- UniProtKB/TrEMBL
- B4DZE2, E5KR06
- Related
- ENSP00000291270.4, ENST00000291270.9
- Conserved Domains (2) summary
-
- pfam08826
Location:470 → 530
- DMPK_coil; DMPK coiled coil domain like
- cd05597
Location:69 → 406
- STKc_DMPK_like; Catalytic domain of Myotonic Dystrophy protein kinase (DMPK)-like Serine/Threonine Kinases
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
45769717..45782490 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
48597252..48609980 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)