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    MYPOP Myb related transcription factor, partner of profilin [ Homo sapiens (human) ]

    Gene ID: 339344, updated on 27-Nov-2024

    Summary

    Official Symbol
    MYPOPprovided by HGNC
    Official Full Name
    Myb related transcription factor, partner of profilinprovided by HGNC
    Primary source
    HGNC:HGNC:20178
    See related
    Ensembl:ENSG00000176182 MIM:617861; AllianceGenome:HGNC:20178
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    P42pop
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in brain (RPKM 2.5), spleen (RPKM 2.4) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See MYPOP in Genome Data Viewer
    Location:
    19q13.32
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (45890023..45902613, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (48717466..48730055, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (46393281..46405871, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10801 Neighboring gene HNF4 motif-containing MPRA enhancer 173 Neighboring gene forkhead box A3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:46385156-46385708 Neighboring gene HNF1 motif-containing MPRA enhancer 100 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:46386261-46386812 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:46386813-46387364 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10802 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10803 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14826 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14827 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14828 Neighboring gene interferon regulatory factor 2 binding protein 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14829 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10804 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14830 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10805 Neighboring gene nanos C2HC-type zinc finger 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:46430224-46430724 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14831 Neighboring gene CRISPR/Cas9-targeted silencer 7 Neighboring gene NOVA alternative splicing regulator 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:46455793-46456740 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr19:46463595-46464168

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    myb-related transcription factor, partner of profilin
    Names
    myb-related protein p42POP
    p42 Myb-related transcription factor, partner of profilin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012643.4NP_001012661.1  myb-related transcription factor, partner of profilin

      See identical proteins and their annotated locations for NP_001012661.1

      Status: VALIDATED

      Source sequence(s)
      AC008623, BC044311, BU196283
      Consensus CDS
      CCDS33055.1
      UniProtKB/Swiss-Prot
      Q86VE0
      Related
      ENSP00000325402.4, ENST00000322217.6
      Conserved Domains (1) summary
      pfam13873
      Location:1692
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      45890023..45902613 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047438749.1XP_047294705.1  myb-related transcription factor, partner of profilin isoform X1

    2. XM_047438750.1XP_047294706.1  myb-related transcription factor, partner of profilin isoform X2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      48717466..48730055 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054320826.1XP_054176801.1  myb-related transcription factor, partner of profilin isoform X1