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    flp-21 GLGPRPLRF-amide [ Caenorhabditis elegans ]

    Gene ID: 182944, updated on 9-Dec-2024

    Summary

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    Official Symbol
    flp-21
    Official Full Name
    GLGPRPLRF-amide
    Primary source
    WormBase:WBGene00001464
    Locus tag
    CELE_C26F1.10
    See related
    AllianceGenome:WB:WBGene00001464
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables neuropeptide Y receptor binding activity. Involved in feeding behavior; neuropeptide signaling pathway; and sleep. Predicted to be located in extracellular space. Is expressed in several structures, including P6; P7; P9; and nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See flp-21 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (7793367..7794025)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene Neuropeptide-Like Protein Neighboring gene UV-stimulated scaffold protein A homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Engineering bacteria to form a biofilm and induce clumping in Caenorhabditis elegans. Dorado-Morales P, et al. ACS Synth Biol, 2014 Dec 19. PMID 24933529
    2. A neuropeptide modulates sensory perception in the entomopathogenic nematode Steinernema carpocapsae. Morris R, et al. PLoS Pathog, 2017 Mar. PMID 28253355, Free PMC Article
    3. Pheromone-based communication influences the production of somatic extracellular vesicles in C. elegans. Szczepańska A, et al. Nat Commun, 2024 Mar 28. PMID 38548742, Free PMC Article
    4. A gene involved in nematode feeding behaviour. Sawarkar R. J Biosci, 2004 Mar. PMID 15295205
    5. NMR analysis of Caenorhabditis elegans FLP-18 neuropeptides: implications for NPR-1 activation. Dossey AT, et al. Biochemistry, 2006 Jun 20. PMID 16768454, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables neuropeptide Y receptor binding IC
    Inferred by Curator
    more info
    		 PubMed 
    enables neuropeptide Y receptor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in feeding behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in sleep IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular space IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GLGPRPLRF-amide
    NP_505011.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7793367..7794025
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072610.7 → NP_505011.2  GLGPRPLRF-amide [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505011.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18234
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q18234.2

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