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    Y49F6B.9 RBR-type E3 ubiquitin transferase [ Caenorhabditis elegans ]

    Gene ID: 173694, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y49F6B.9
    Official Full Name
    RBR-type E3 ubiquitin transferase
    Primary source
    WormBase:WBGene00021721
    Locus tag
    CELE_Y49F6B.9
    See related
    AllianceGenome:WB:WBGene00021721
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human RNF19A (ring finger protein 19A, RBR E3 ubiquitin protein ligase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y49F6B.9 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    10
    Sequence:
    Chromosome: II; NC_003280.10 (3493907..3499387, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Smu-2 suppressor of mec-8 and unc-52 protein Neighboring gene F-box domain-containing protein Neighboring gene Cuticle collagen 71 Neighboring gene ncRNA Neighboring gene Fcf2 pre-rRNA processing C-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin conjugating enzyme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RBR-type E3 ubiquitin transferase
    NP_001040825.2
    • Confirmed by transcript evidence
    NP_001040826.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      3493907..3499387 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047360.5 → NP_001040825.2  RBR-type E3 ubiquitin transferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040825.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DJA6
      Conserved Domains (1) summary
      smart00647
      Location:111 → 176
      IBR; In Between Ring fingers

    2. NM_001047361.6 → NP_001040826.2  RBR-type E3 ubiquitin transferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040826.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8DJA7
      Conserved Domains (1) summary
      smart00647
      Location:74 → 139
      IBR; In Between Ring fingers
    Nucleotide Protein
    Heading Accession and Version

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