ugt-46 Putative UDP-glucuronosyltransferase ugt-46;glucuronosyltransferase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ugt-46
Official Full Name: Putative UDP-glucuronosyltransferase ugt-46;glucuronosyltransferase
Primary source: WormBase:WBGene00015141
Locus tag: CELE_B0310.5
See related: AllianceGenome:WB:WBGene00015141
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to several human genes including UGT2A2 (UDP glucuronosyltransferase family 2 member A2); UGT8 (UDP glycosyltransferase 8); and UGT3A1 (UDP glycosyltransferase family 3 member A1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ugt-46 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 10

Sequence:: Chromosome: X; NC_003284.9 (525928..530289, complement)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

B0310.5 (e-PCR)
- UniSTS:313390

B0310.6 (e-PCR)
- UniSTS:320832

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables UDP-glycosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glucuronosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Putative UDP-glucuronosyltransferase ugt-46;glucuronosyltransferase

NP_001380233.1

Partially confirmed by transcript evidence

NP_508112.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

525928..530289 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_075711.7 → NP_508112.1 Putative UDP-glucuronosyltransferase ugt-46 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_508112.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q10941

Conserved Domains (2) summary

PHA03392
Location:213 → 503

egt; ecdysteroid UDP-glucosyltransferase; Provisional

pfam00201
Location:19 → 527

UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
NM_001392716.1 → NP_001380233.1 glucuronosyltransferase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A2K5ATY0

Conserved Domains (1) summary

cl10013
Location:18 → 170

Glycosyltransferase_GTB-type; glycosyltransferase family 1 and related proteins with GTB topology