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    F37H8.5 GILT-like protein F37H8.5 [ Caenorhabditis elegans ]

    Gene ID: 3564874, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F37H8.5
    Official Full Name
    GILT-like protein F37H8.5
    Primary source
    WormBase:WBGene00009514
    Locus tag
    CELE_F37H8.5
    See related
    AllianceGenome:WB:WBGene00009514
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity. Located in cytoplasm. Is expressed in intestine; nervous system; rectal gland cell; and reproductive system. Orthologous to human IFI30 (IFI30 lysosomal thiol reductase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F37H8.5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (11188206..11189437)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene HAD family phosphatase Neighboring gene Transcription factor lir-3 Neighboring gene Sidoreflexin Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension. Gao K, et al. Elife, 2019 Jan 15. PMID 30642431, Free PMC Article
    2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    3. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    4. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GILT-like protein F37H8.5
    NP_496397.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11188206..11189437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063996.4 → NP_496397.1  GILT-like protein F37H8.5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496397.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O17861
      Conserved Domains (1) summary
      pfam03227
      Location:77 → 182
      GILT; Gamma interferon inducible lysosomal thiol reductase (GILT)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O17861.1

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