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    C05C8.5 Exonuclease domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179116, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C05C8.5
    Official Full Name
    Exonuclease domain-containing protein
    Primary source
    WormBase:WBGene00015462
    Locus tag
    CELE_C05C8.5
    See related
    AllianceGenome:WB:WBGene00015462
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable exonuclease activity. Predicted to be involved in rRNA 3'-end processing. Predicted to be active in nucleus. Orthologous to human REXO5 (RNA exonuclease 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C05C8.5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (7232673..7234826, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene peptidylprolyl isomerase Neighboring gene GEX Interacting protein Neighboring gene KRR1 small subunit processome component Neighboring gene BTB/POZ domain-containing protein 9 Neighboring gene Centriolar and ciliogenesis-associated protein hyls-1;Hydrolethalus syndrome protein 1 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables exonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables exonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Exonuclease domain-containing protein
    NP_504838.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7232673..7234826 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072437.8 → NP_504838.1  Exonuclease domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504838.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16312
      Conserved Domains (1) summary
      cd06145
      Location:222 → 372
      REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins
    Nucleotide Protein
    Heading Accession and Version

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