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    ensh-1 Fibrinogen C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181135, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ensh-1
    Official Full Name
    Fibrinogen C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00017013
    Locus tag
    CELE_D1009.3
    See related
    AllianceGenome:WB:WBGene00017013
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in familial hypobetalipoproteinemia 2. Orthologous to several human genes including ANGPTL3 (angiopoietin like 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ensh-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Sequence:
    Chromosome: X; NC_003284.9 (8905389..8910838)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Separase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Peptidyl-prolyl cis-trans isomerase 8 Neighboring gene Neuropeptide-Like Protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Fibrinogen C-terminal domain-containing protein
    NP_001024508.1
    • Confirmed by transcript evidence
    NP_001024509.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8905389..8910838
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029338.7 → NP_001024509.1  Fibrinogen C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024509.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYR5
      Conserved Domains (1) summary
      smart00186
      Location:218 → 458
      FBG; Fibrinogen-related domains (FReDs)

    2. NM_001029337.4 → NP_001024508.1  Fibrinogen C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024508.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18914
      Conserved Domains (1) summary
      smart00186
      Location:220 → 460
      FBG; Fibrinogen-related domains (FReDs)
    Nucleotide Protein
    Heading Accession and Version

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