U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    acin-1 SAP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172030, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    acin-1
    Official Full Name
    SAP domain-containing protein
    Primary source
    WormBase:WBGene00016601
    Locus tag
    CELE_C43E11.1
    See related
    AllianceGenome:WB:WBGene00016601
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Involved in gonad morphogenesis and regulation of cell migration. Predicted to be part of ASAP complex. Orthologous to human ACIN1 (apoptotic chromatin condensation inducer 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See acin-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    12
    Sequence:
    Chromosome: I; NC_003279.8 (4270666..4273336)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Crossover junction endonuclease MUS81 Neighboring gene 60S ribosome subunit biogenesis protein NIP7 homolog Neighboring gene Cell division control protein Neighboring gene PEST proteolytic signal-containing nuclear protein Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The conserved oligomeric Golgi complex acts in organ morphogenesis via glycosylation of an ADAM protease in C. elegans. Kubota Y, et al. Development, 2006 Jan. PMID 16354716
    2. The TORC1 phosphoproteome in C. elegans reveals roles in transcription and autophagy. Sewell AK, et al. iScience, 2022 May 20. PMID 35479415, Free PMC Article
    3. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article
    4. Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly. Schaan Profes M, et al. PLoS Biol, 2024 Jan. PMID 38252619, Free PMC Article
    5. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in gonad morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ASAP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    SAP domain-containing protein
    NP_491344.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4270666..4273336
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058943.7 → NP_491344.1  SAP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491344.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91156
      Conserved Domains (4) summary
      smart00513
      Location:13 → 47
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      cd12432
      Location:293 → 381
      RRM_ACINU; RNA recognition motif in apoptotic chromatin condensation inducer in the nucleus (acinus) and similar proteins
      pfam09184
      Location:154 → 242
      PPP4R2; PPP4R2
      pfam16294
      Location:468 → 550
      RSB_motif; RNSP1-SAP18 binding (RSB) motif
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.