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    igcm-1 B-cell receptor CD22-like [ Caenorhabditis elegans ]

    Gene ID: 180433, updated on 9-Dec-2024

    Summary

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    Official Symbol
    igcm-1
    Official Full Name
    B-cell receptor CD22-like
    Primary source
    WormBase:WBGene00018215
    Locus tag
    CELE_F39H12.4
    See related
    AllianceGenome:WB:WBGene00018215
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. Predicted to be active in cell-cell junction and plasma membrane. Is expressed in arcade cell; intestine; nervous system; pharyngeal cell; and seam cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See igcm-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    16
    Sequence:
    Chromosome: X; NC_003284.9 (845731..851521, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Pericentrin Neighboring gene RIIa domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SAX-7/L1CAM and HMR-1/cadherin function redundantly in blastomere compaction and non-muscle myosin accumulation during Caenorhabditis elegans gastrulation. Grana TM, et al. Dev Biol, 2010 Aug 15. PMID 20515680, Free PMC Article
    2. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell-cell junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    B-cell receptor CD22-like
    NP_508166.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      845731..851521 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075765.8 → NP_508166.1  B-cell receptor CD22-like [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508166.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TXI8
      Conserved Domains (7) summary
      cd00096
      Location:537 → 615
      Ig; Immunoglobulin domain
      smart00408
      Location:646 → 719
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:644 → 728
      IG_like; Immunoglobulin like
      cd00063
      Location:733 → 843
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam13895
      Location:429 → 513
      Ig_2; Immunoglobulin domain
      pfam13927
      Location:245 → 316
      Ig_3; Immunoglobulin domain
      cl11960
      Location:146 → 226
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version

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