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    spe-19 CX domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190958, updated on 9-Dec-2024

    Summary

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    Official Symbol
    spe-19
    Official Full Name
    CX domain-containing protein
    Primary source
    WormBase:WBGene00013747
    Locus tag
    CELE_Y113G7A.10
    See related
    AllianceGenome:WB:WBGene00013747
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in spermatid development. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See spe-19 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (20040949..20047410, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Ligand-Gated ion Channel Neighboring gene ncRNA Neighboring gene Ashwin Neighboring gene pseudo Neighboring gene Serpentine Receptor, class H Neighboring gene Homeobox protein ttx-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SPE-8, a protein-tyrosine kinase, localizes to the spermatid cell membrane through interaction with other members of the SPE-8 group spermatid activation signaling pathway in C. elegans. Muhlrad PJ, et al. BMC Genet, 2014 Jul 14. PMID 25022984, Free PMC Article
    2. Spatial Transcriptomics of Nematodes Identifies Sperm Cells as a Source of Genomic Novelty and Rapid Evolution. Rödelsperger C, et al. Mol Biol Evol, 2021 Jan 4. PMID 32785688, Free PMC Article
    3. The genetic and molecular analysis of spe-19, a gene required for sperm activation in Caenorhabditis elegans. Geldziler B, et al. Dev Biol, 2005 Jul 15. PMID 15939418
    4. Caenorhabditis elegans sperm membrane protein interactome. Marcello MR, et al. Biol Reprod, 2018 Jun 1. PMID 29546388, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SPE-19 is a candidate for the receptor/co-receptor necessary for the transduction of the activation signal across the sperm plasma membrane.
      Title: The genetic and molecular analysis of spe-19, a gene required for sperm activation in Caenorhabditis elegans.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CX domain-containing protein
    NP_507871.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      20040949..20047410 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075470.5 → NP_507871.3  CX domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507871.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U2Y6
    Nucleotide Protein
    Heading Accession and Version

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