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    ZK686.2 Putative ATP-dependent RNA helicase ZK686.2 [ Caenorhabditis elegans ]

    Gene ID: 176088, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ZK686.2
    Official Full Name
    Putative ATP-dependent RNA helicase ZK686.2
    Primary source
    WormBase:WBGene00022792
    Locus tag
    CELE_ZK686.2
    See related
    AllianceGenome:WB:WBGene00022792
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be located in P granule. Predicted to be active in nucleus. Is expressed in neurons. Orthologous to human DDX51 (DEAD-box helicase 51). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ZK686.2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (7763720..7766052, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Putative serine protease pcp-1 Neighboring gene Metaxin-2 homolog Neighboring gene Putative zinc finger protein ZK686.5 Neighboring gene putative dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in P granule IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Putative ATP-dependent RNA helicase ZK686.2
    NP_498690.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7763720..7766052 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066289.7 → NP_498690.2  Putative ATP-dependent RNA helicase ZK686.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498690.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34668
      Conserved Domains (3) summary
      smart00487
      Location:130 → 352
      DEXDc; DEAD-like helicases superfamily
      cd00079
      Location:371 → 502
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      pfam00270
      Location:135 → 330
      DEAD; DEAD/DEAH box helicase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34668.2

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