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    ins-22 putative insulin-like peptide alpha-type 2 [ Caenorhabditis elegans ]

    Gene ID: 191690, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ins-22
    Official Full Name
    putative insulin-like peptide alpha-type 2
    Primary source
    WormBase:WBGene00002105
    Locus tag
    CELE_M04D8.2
    See related
    AllianceGenome:WB:WBGene00002105
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in extracellular region. Is expressed in nervous system; pharynx; rectum; and vulval muscle. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ins-22 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003281.10 (10026289..10026686)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene putative insulin-like peptide alpha-type 1 Neighboring gene putative insulin-like peptide alpha-type 3 Neighboring gene RDD domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A tonically active master neuron modulates mutually exclusive motor states at two timescales. Meng J, et al. Sci Adv, 2024 Apr 12. PMID 38598630, Free PMC Article
    2. Gold Nanoparticles Reduce Food Sensation in Caenorhabditis elegans via the Voltage-Gated Channel EGL-19. Wang M, et al. Int J Nanomedicine, 2023. PMID 37020688, Free PMC Article
    3. Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons. Goodwin PR, et al. J Neurosci, 2012 Jun 13. PMID 22699897, Free PMC Article
    4. The scaffolding protein SYD-2/Liprin-α regulates the mobility and polarized distribution of dense-core vesicles in C. elegans motor neurons. Goodwin PR, et al. PLoS One, 2013. PMID 23358451, Free PMC Article
    5. Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. Pierce SB, et al. Genes Dev, 2001 Mar 15. PMID 11274053, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative insulin-like peptide alpha-type 2
    NP_499223.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10026289..10026686
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066822.5 → NP_499223.1  putative insulin-like peptide alpha-type 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499223.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21508
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q21508.1

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