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    F13E6.2 Adenylate kinase isoenzyme 5 [ Caenorhabditis elegans ]

    Gene ID: 181264, updated on 27-Dec-2024

    Summary

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    Official Symbol
    F13E6.2
    Official Full Name
    Adenylate kinase isoenzyme 5
    Primary source
    WormBase:WBGene00008746
    Locus tag
    CELE_F13E6.2
    See related
    AllianceGenome:WB:WBGene00008746
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable adenylate kinase activity. Predicted to be involved in ADP biosynthetic process. Predicted to be active in mitochondrion. Orthologous to human AK5 (adenylate kinase 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F13E6.2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    19
    Sequence:
    Chromosome: X; NC_003284.9 (10668162..10674299, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tRNA-Glu Neighboring gene tRNA-Glu Neighboring gene Uncharacterized protein Neighboring gene Zinc finger PHD-type domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables adenylate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleobase-containing compound kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ADP biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nucleobase-containing compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleoside monophosphate phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Adenylate kinase isoenzyme 5
    NP_509786.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      10668162..10674299 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077385.6 → NP_509786.2  Adenylate kinase isoenzyme 5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509786.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EC85
      Conserved Domains (2) summary
      TIGR01360
      Location:514 → 699
      aden_kin_iso1; adenylate kinase, isozyme 1 subfamily
      cd01428
      Location:515 → 690
      ADK; Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for ...
    Nucleotide Protein
    Heading Accession and Version

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