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    srx-43 Serpentine receptor class X-43 [ Caenorhabditis elegans ]

    Gene ID: 188374, updated on 9-Dec-2024

    Summary

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    Official Symbol
    srx-43
    Official Full Name
    Serpentine receptor class X-43
    Primary source
    WormBase:WBGene00005934
    Locus tag
    CELE_T10C6.3
    See related
    AllianceGenome:WB:WBGene00005934
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables pheromone receptor activity. Involved in calcium-mediated signaling; cellular response to pheromone; and locomotory exploration behavior. Located in non-motile cilium and perikaryon. Is expressed in ASIL and ASIR. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See srx-43 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (16017971..16020066)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Seven TM Receptor Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein Neighboring gene Spliceosome-associated protein CWC15 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulatory changes in two chemoreceptor genes contribute to a Caenorhabditis elegans QTL for foraging behavior. Greene JS, et al. Elife, 2016 Nov 28. PMID 27893361, Free PMC Article
    2. Balancing selection shapes density-dependent foraging behaviour. Greene JS, et al. Nature, 2016 Nov 10. PMID 27799655, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pheromone receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in calcium-mediated signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to pheromone IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in locomotory exploration behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in non-motile cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in perikaryon IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in perikaryon IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Serpentine receptor class X-43
    NP_507022.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      16017971..16020066
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074621.3 → NP_507022.2  Serpentine receptor class X-43 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507022.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O45767
      UniProtKB/TrEMBL
      A0A1J0F945
      Conserved Domains (1) summary
      cl21561
      Location:33 → 299
      7tm_4; Olfactory receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O45767.2

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