F57B10.8 Activator of basal transcription 1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F57B10.8
Official Full Name: Activator of basal transcription 1
Primary source: WormBase:WBGene00019005
Locus tag: CELE_F57B10.8
See related: AllianceGenome:WB:WBGene00019005
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleus. Predicted to be active in nucleolus. Orthologous to human ABT1 (activator of basal transcription 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F57B10.8 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 6

Sequence:: Chromosome: I; NC_003279.8 (6548676..6550436, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F57B10.9 (e-PCR)
- UniSTS:311899

F57B10.8 (e-PCR)
- UniSTS:306826

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
involved_in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA Inferred from Biological aspect of Ancestor more info
involved_in small-subunit processome assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Activator of basal transcription 1

NP_491887.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

6548676..6550436 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059486.7 → NP_491887.1 Activator of basal transcription 1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_491887.1

Status: REVIEWED

UniProtKB/TrEMBL

O44734

Conserved Domains (1) summary

cl17169
Location:82 → 172

RRM_SF; RNA recognition motif (RRM) superfamily