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    sra-11 Serpentine receptor class alpha-11 [ Caenorhabditis elegans ]

    Gene ID: 191782, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sra-11
    Official Full Name
    Serpentine receptor class alpha-11
    Primary source
    WormBase:WBGene00005037
    Locus tag
    CELE_F44F4.13
    See related
    AllianceGenome:WB:WBGene00005037
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception and olfactory learning. Predicted to be located in membrane. Is expressed in intestine and nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sra-11 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (10908808..10910319, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Core-2/I-Branching enzyme Neighboring gene Serpentine receptor class alpha-12 Neighboring gene Ovule protein;Transmembrane protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Levin ED, et al. , 2006. PMID 21204358
    2. An interneuronal chemoreceptor required for olfactory imprinting in C. elegans. Remy JJ, et al. Science, 2005 Jul 29. PMID 16051801
    3. Activation of G(αq) Signaling Enhances Memory Consolidation and Slows Cognitive Decline. Arey RN, et al. Neuron, 2018 May 2. PMID 29656871, Free PMC Article
    4. Regulation of longevity by genes required for the functions of AIY interneuron in nematode Caenorhabditis elegans. Shen L, et al. Mech Ageing Dev, 2010 Nov-Dec. PMID 21055415
    5. Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene. Hobert O, et al. Neuron, 1997 Aug. PMID 9292724

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane signaling receptor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in olfactory learning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of chemical stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Serpentine receptor class alpha-11
    NP_496348.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10908808..10910319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063947.2 → NP_496348.2  Serpentine receptor class alpha-11 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496348.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20411
      Conserved Domains (1) summary
      pfam02117
      Location:3 → 332
      7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q20411.2

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