argk-1 arginine kinase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: argk-1
Official Full Name: arginine kinase
Primary source: WormBase:WBGene00009706
Locus tag: CELE_F44G3.2
See related: AllianceGenome:WB:WBGene00009706
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable kinase activity. Involved in ATP metabolic process and generation of precursor metabolites and energy. Predicted to be active in extracellular space. Is expressed in IL socket cell; OL socket cell; and intestine. Orthologous to several human genes including CKB (creatine kinase B); CKM (creatine kinase, M-type); and CKMT1A (creatine kinase, mitochondrial 1A). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

ARGK-1 is a longevity effector in C. elegans with reduced RSKS-1/S6K levels.
Title: C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables arginine kinase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables creatine kinase activity	IEA Inferred from Electronic Annotation more info
enables kinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity, transferring phosphorus-containing groups	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ATP metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in generation of precursor metabolites and energy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in phosphocreatine biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

NP_507054.1

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