rab-21 Ras-related protein Rab-21 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rab-21
Official Full Name: Ras-related protein Rab-21
Primary source: WormBase:WBGene00004279
Locus tag: CELE_T01B7.3
See related: AllianceGenome:WB:WBGene00004279
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport. Predicted to be active in early endosome. Orthologous to human RAB21 (RAB21, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rab-21 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 4

Sequence:: Chromosome: II; NC_003280.10 (8713998..8715013, complement)

Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T01B7.4 (e-PCR)
- UniSTS:317736

T01B7.3 (e-PCR)
- UniSTS:317025

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in early endosome	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Ras-related protein Rab-21

NP_495854.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003280.10 Reference assembly

Range

8713998..8715013 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_063453.5 → NP_495854.1 Ras-related protein Rab-21 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_495854.1

Status: REVIEWED

UniProtKB/TrEMBL

I7F498, Q22045

Conserved Domains (2) summary

cd04123
Location:13 → 174

Rab21; Rab GTPase family 21 (Rab21)

pfam00071
Location:14 → 175

Ras; Ras family