ucr-2.3 Peptidase M16 N-terminal domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ucr-2.3
Official Full Name: Peptidase M16 N-terminal domain-containing protein
Primary source: WormBase:WBGene00020757
Locus tag: CELE_T24C4.1
See related: AllianceGenome:WB:WBGene00020757
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable metalloendopeptidase activity. Involved in protein folding. Predicted to be active in mitochondrial matrix. Is expressed in neurons and pharyngeal gland cell. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 5. Orthologous to human UQCRC2 (ubiquinol-cytochrome c reductase core protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ucr-2.3 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (879860..881458)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T24C4.1 (e-PCR)
- UniSTS:312775

T24C4.5 (e-PCR)
- UniSTS:312776

F58A4.4 (e-PCR)
- UniSTS:321525

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables metalloendopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein folding	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein processing	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Peptidase M16 N-terminal domain-containing protein

NP_497284.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

879860..881458

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_064883.8 → NP_497284.1 Peptidase M16 N-terminal domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_497284.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9TZ33

Conserved Domains (1) summary

COG0612
Location:1 → 422

PqqL; Predicted Zn-dependent peptidase [General function prediction only]