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    Y42H9AR.1 PDZ GRASP-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177604, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y42H9AR.1
    Official Full Name
    PDZ GRASP-type domain-containing protein
    Primary source
    WormBase:WBGene00021536
    Locus tag
    CELE_Y42H9AR.1
    See related
    AllianceGenome:WB:WBGene00021536
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in Golgi organization. Predicted to be active in Golgi apparatus. Orthologous to several human genes including GORASP2 (golgi reassembly stacking protein 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y42H9AR.1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (8113495..8115673)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene FMRF-Like Peptide Neighboring gene FYVE-type domain-containing protein Neighboring gene ELM2 domain-containing protein Neighboring gene Receptor L-domain domain-containing protein Neighboring gene Serine/threonine-protein phosphatase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    2. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    3. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    4. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PDZ GRASP-type domain-containing protein
    NP_001370725.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8113495..8115673
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383134.2 → NP_001370725.1  PDZ GRASP-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3Y1
      Conserved Domains (3) summary
      PHA03247
      Location:201 → 506
      PHA03247; large tegument protein UL36; Provisional
      pfam04495
      Location:70 → 204
      GRASP55_65; GRASP55/65 PDZ-like domain
      cl00117
      Location:14 → 100
      PDZ; PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
    Nucleotide Protein
    Heading Accession and Version

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