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    his-64 Histone H4 [ Caenorhabditis elegans ]

    Gene ID: 178066, updated on 9-Dec-2024

    Summary

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    Official Symbol
    his-64
    Official Full Name
    Histone H4
    Primary source
    WormBase:WBGene00001938
    Locus tag
    CELE_F22B3.1
    See related
    AllianceGenome:WB:WBGene00001938
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Involved in positive regulation of transcription by RNA polymerase II. Is expressed in several structures, including germ line; head; intestine; pharynx; and somatic cell. Orthologous to several human genes including H4C1 (H4 clustered histone 1); H4C11 (H4 clustered histone 11); and H4C12 (H4 clustered histone 12). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See his-64 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_003282.8 (11407116..11407427)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Histone H3 Neighboring gene ncRNA Neighboring gene glutamine--fructose-6-phosphate transaminase (isomerizing) Neighboring gene PAN-3 domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Three-dimensional distributions of elements in biological samples by energy-filtered electron tomography. Leapman RD, et al. Ultramicroscopy, 2004 Jul. PMID 15219696
    2. Natural variation in the response of Caenorhabditis elegans towards Bacillus thuringiensis. Schulenburg H, et al. Parasitology, 2004 Apr. PMID 15151149
    3. Annotation transfer between genomes: protein-protein interologs and protein-DNA regulogs. Yu H, et al. Genome Res, 2004 Jun. PMID 15173116, Free PMC Article
    4. Hypoxia-inducible Factor-1 (HIF-1)-independent hypoxia response of the small heat shock protein hsp-16.1 gene regulated by chromatin-remodeling factors in the nematode Caenorhabditis elegans. Lee J, et al. J Biol Chem, 2013 Jan 18. PMID 23229554, Free PMC Article
    5. Reference quantitative transcriptome dataset for adult Caenorhabditis elegans. Piovesan A, et al. Data Brief, 2019 Aug. PMID 31440537, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Histone H4
    NP_502154.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11407116..11407427
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069753.5 → NP_502154.1  Histone H4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502154.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O02619, P02306, P18678, P62784, Q7JNV2
      Conserved Domains (1) summary
      PLN00035
      Location:1 → 103
      PLN00035; histone H4; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P62784.2

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