F52C12.2 18S rRNA aminocarboxypropyltransferase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: F52C12.2
Official Full Name: 18S rRNA aminocarboxypropyltransferase
Primary source: WormBase:WBGene00018679
Locus tag: CELE_F52C12.2
See related: AllianceGenome:WB:WBGene00018679
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable 18S rRNA aminocarboxypropyltransferase activity and S-adenosyl-L-methionine binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in cytoplasm. Orthologous to human TSR3 (TSR3 ribosome maturation factor). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See F52C12.2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 3

Sequence:: Chromosome: IV; NC_003282.8 (1953579..1956710)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F52C12.3 (e-PCR)
- UniSTS:322161

F52C12.2 (e-PCR)
- UniSTS:319380

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables 18S rRNA aminocarboxypropyltransferase activity	IEA Inferred from Electronic Annotation more info
enables S-adenosyl-L-methionine binding	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in enzyme-directed rRNA pseudouridine synthesis	IEA Inferred from Electronic Annotation more info
involved_in maturation of SSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info
involved_in rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 18S rRNA aminocarboxypropyltransferase

NP_001379972.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

1953579..1956710

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001392260.1 → NP_001379972.1 18S rRNA aminocarboxypropyltransferase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

Q95X18

Conserved Domains (2) summary

pfam04034
Location:99 → 224

Ribo_biogen_C; Ribosome biogenesis protein, C-terminal

pfam04068
Location:61 → 95

RLI; Possible Fer4-like domain in RNase L inhibitor, RLI