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    coa-7 Cytochrome c oxidase assembly factor 7 homolog [ Caenorhabditis elegans ]

    Gene ID: 174784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    coa-7
    Official Full Name
    Cytochrome c oxidase assembly factor 7 homolog
    Primary source
    WormBase:WBGene00013925
    Locus tag
    CELE_ZK20.4
    See related
    AllianceGenome:WB:WBGene00013925
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be active in mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in spinocerebellar ataxia with axonal neuropathy type 3. Orthologous to human COA7 (cytochrome c oxidase assembly factor 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See coa-7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (11649096..11651148, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Glycoprotein Hormone (FLR-2) Interacting protein Neighboring gene UV excision repair protein RAD23 Neighboring gene 26S proteasome non-ATPase regulatory subunit 8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Cytochrome c oxidase assembly factor 7 homolog
    NP_496487.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11649096..11651148 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064086.5 → NP_496487.1  Cytochrome c oxidase assembly factor 7 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496487.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q23450
      Conserved Domains (2) summary
      COG0790
      Location:48 → 231
      TPR; TPR repeat [Signal transduction mechanisms]
      sd00010
      Location:128 → 156
      SLR; SLR repeat [structural motif]

    RNA

    1. NR_024299.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q23450.1

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