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    F44G4.1 Brix domain-containing protein F44G4.1 [ Caenorhabditis elegans ]

    Gene ID: 174434, updated on 9-Dec-2024

    Summary

    Official Symbol
    F44G4.1
    Official Full Name
    Brix domain-containing protein F44G4.1
    Primary source
    WormBase:WBGene00009711
    Locus tag
    CELE_F44G4.1
    See related
    AllianceGenome:WB:WBGene00009711
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable rRNA primary transcript binding activity. Predicted to be involved in maturation of 5.8S rRNA and maturation of LSU-rRNA. Predicted to be part of preribosome, large subunit precursor. Predicted to be active in nucleolus. Orthologous to human RPF1 (ribosome production factor 1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See F44G4.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (8994636..8996269)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene MARVEL domain-containing protein Neighboring gene Torsin-like protein Neighboring gene putative NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial Neighboring gene Uncharacterized protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables rRNA primary transcript binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in maturation of 5.8S rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in maturation of LSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Brix domain-containing protein F44G4.1
    NP_495918.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8994636..8996269
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063517.8NP_495918.1  Brix domain-containing protein F44G4.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495918.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54073, Q20418
      Conserved Domains (1) summary
      smart00879
      Location:180349
      Brix; The Brix domain is found in a number of eukaryotic proteins