tomm-40 Mitochondrial import receptor subunit TOM40 homolog [Caenorhabditis elegans] - Gene

Summary

Official Symbol: tomm-40
Official Full Name: Mitochondrial import receptor subunit TOM40 homolog
Primary source: WormBase:WBGene00007686
Locus tag: CELE_C18E9.6
See related: AllianceGenome:WB:WBGene00007686
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable protein transmembrane transporter activity. Involved in protein import into mitochondrial matrix. Located in mitochondrial membrane. Is expressed in several structures, including hypodermis; intestine; nervous system; non-striated muscle; and pharynx. Human ortholog(s) of this gene implicated in cerebral infarction. Orthologous to human TOMM40 (translocase of outer mitochondrial membrane 40) and TOMM40L (translocase of outer mitochondrial membrane 40 like). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables porin activity	IEA Inferred from Electronic Annotation more info
enables protein transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in monoatomic ion transport	IEA Inferred from Electronic Annotation more info
involved_in protein import into mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein import into mitochondrial matrix	IEA Inferred from Electronic Annotation more info
involved_in protein import into mitochondrial matrix	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein targeting to mitochondrion	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial outer membrane translocase complex	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of pore complex	IEA Inferred from Electronic Annotation more info

NP_495912.1

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The following sections contain reference sequences that belong to a specific genome build. Explain