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    W02B12.1 Lipase_GDSL domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174746, updated on 9-Dec-2024

    Summary

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    Official Symbol
    W02B12.1
    Official Full Name
    Lipase_GDSL domain-containing protein
    Primary source
    WormBase:WBGene00012201
    Locus tag
    CELE_W02B12.1
    See related
    AllianceGenome:WB:WBGene00012201
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phospholipase activity. Predicted to be involved in phospholipid metabolic process. Orthologous to human PLB1 (phospholipase B1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See W02B12.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    10
    Sequence:
    Chromosome: II; NC_003280.10 (11449021..11451445)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Secreted protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene putative splicing factor, arginine/serine-rich 2 Neighboring gene putative splicing factor, arginine/serine-rich 1 Neighboring gene pseudo Neighboring gene Alanine--tRNA ligase, mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity, acting on ester bonds IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phospholipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phospholipase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phospholipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Lipase_GDSL domain-containing protein
    NP_496440.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11449021..11451445
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064039.7 → NP_496440.1  Lipase_GDSL domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496440.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23119
      Conserved Domains (1) summary
      cd01824
      Location:41 → 338
      Phospholipase_B_like; Phospholipase-B_like. This subgroup of the SGNH-family of lipolytic enzymes may have both esterase and phospholipase-A/lysophospholipase activity. It's members may be involved in the conversion of phosphatidylcholine to fatty acids and ...
    Nucleotide Protein
    Heading Accession and Version

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