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    ckc-1 ethanolamine kinase [ Caenorhabditis elegans ]

    Gene ID: 188971, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ckc-1
    Official Full Name
    ethanolamine kinase
    Primary source
    WormBase:WBGene00000515
    Locus tag
    CELE_T27A10.3
    See related
    AllianceGenome:WB:WBGene00000515
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ethanolamine kinase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be active in cytoplasm. Orthologous to several human genes including ETNK2 (ethanolamine kinase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ckc-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (3576608..3578830)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Vitellogenin-3 Neighboring gene ncRNA Neighboring gene GST N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple isoforms of choline kinase from Caenorhabditis elegans: cloning, expression, purification, and characterization. Gee P, et al. Biochim Biophys Acta, 2003 May 30. PMID 12758145
    2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ethanolamine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphatidylethanolamine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ethanolamine kinase
    NP_001024929.1
    • Confirmed by transcript evidence
    NP_001024930.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3576608..3578830
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029758.3 → NP_001024929.1  ethanolamine kinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024929.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22820
      Conserved Domains (2) summary
      PLN02236
      Location:24 → 332
      PLN02236; choline kinase
      cd05157
      Location:41 → 332
      ETNK_euk; Euykaryotic Ethanolamine kinase

    2. NM_001029759.6 → NP_001024930.1  ethanolamine kinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024930.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86MJ6
      Conserved Domains (1) summary
      cd05157
      Location:41 → 320
      ETNK_euk; Euykaryotic Ethanolamine kinase
    Nucleotide Protein
    Heading Accession and Version

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