R12A1.3 BPTI/Kunitz inhibitor domain-containing protein;Kunitz/Bovine pancreatic trypsin inhibitor domain protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: R12A1.3
Official Full Name: BPTI/Kunitz inhibitor domain-containing protein;Kunitz/Bovine pancreatic trypsin inhibitor domain protein
Primary source: WormBase:WBGene00020017
Locus tag: CELE_R12A1.3
See related: AllianceGenome:WB:WBGene00020017
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFDC8 (WAP four-disulfide core domain 8). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See R12A1.3 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 6

Sequence:: Chromosome: V; NC_003283.11 (1422787..1425794, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R12A1.3 (e-PCR)
- UniSTS:320124

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables peptidase inhibitor activity	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase inhibitor activity	IBA Inferred from Biological aspect of Ancestor more info
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: BPTI/Kunitz inhibitor domain-containing protein;Kunitz/Bovine pancreatic trypsin inhibitor domain protein

NP_001300177.1

Confirmed by transcript evidence

NP_503410.3

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

1422787..1425794 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_071009.6 → NP_503410.3 Kunitz/Bovine pancreatic trypsin inhibitor domain protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_503410.3

Status: REVIEWED

UniProtKB/TrEMBL

O16701

Conserved Domains (1) summary

pfam00014
Location:161 → 213

Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
NM_001313248.3 → NP_001300177.1 BPTI/Kunitz inhibitor domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A0K3ASA6

Conserved Domains (1) summary

pfam00014
Location:37 → 88

Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain