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    F46C5.6 Serine/threonine-protein phosphatase 4 regulatory subunit 4 [ Caenorhabditis elegans ]

    Gene ID: 174413, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F46C5.6
    Official Full Name
    Serine/threonine-protein phosphatase 4 regulatory subunit 4
    Primary source
    WormBase:WBGene00009781
    Locus tag
    CELE_F46C5.6
    See related
    AllianceGenome:WB:WBGene00009781
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein phosphatase regulator activity. Predicted to be part of protein serine/threonine phosphatase complex. Predicted to be active in cytosol. Is expressed in hypodermis and pharynx. Orthologous to human PPP4R4 (protein phosphatase 4 regulatory subunit 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F46C5.6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    16
    Sequence:
    Chromosome: II; NC_003280.10 (8840200..8844515, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Alanine--glyoxylate aminotransferase Neighboring gene Acyltransferase 3 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans. Gottschalk A, et al. EMBO J, 2005 Jul 20. PMID 15990870, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein serine/threonine phosphatase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Serine/threonine-protein phosphatase 4 regulatory subunit 4
    NP_495884.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8840200..8844515 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063483.6 → NP_495884.3  Serine/threonine-protein phosphatase 4 regulatory subunit 4 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495884.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGI8
      Conserved Domains (3) summary
      COG5657
      Location:233 → 478
      CSE1; CAS/CSE protein involved in chromosome segregation [Cell division and chromosome partitioning]
      pfam15548
      Location:761 → 839
      DUF4655; Domain of unknown function (DUF4655)
      sd00044
      Location:202 → 231
      HEAT; HEAT repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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