Gpr31b G protein-coupled receptor 31, D17Leh66b region [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gpr31bprovided by MGI
Official Full Name: G protein-coupled receptor 31, D17Leh66b regionprovided by MGI
Primary source: MGI:MGI:1354372
See related: Ensembl:ENSMUSG00000071311 AllianceGenome:MGI:1354372
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gpr31; Gpr31c; 12-HETER; GPR31c(t)
Summary: Enables bioactive lipid receptor activity. Involved in several processes, including negative regulation of inflammatory response; response to ischemia; and response to molecule of bacterial origin. Predicted to be located in plasma membrane. Orthologous to human GPR31 (G protein-coupled receptor 31). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human all
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Genomic context

Location:: 17 A1; 17 8.76 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (13270208..13271167, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (13051321..13052280, complement)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3) 1 citation
Targeted (1) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	ISO Inferred from Sequence Orthology more info
enables G protein-coupled receptor activity	ISS Inferred from Sequence or Structural Similarity more info
enables arachidonate binding	IEA Inferred from Electronic Annotation more info
enables arachidonate binding	ISO Inferred from Sequence Orthology more info
enables bioactive lipid receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables bioactive lipid receptor activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in G protein-coupled receptor signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of inflammatory response	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of inflammatory response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of immune response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to acidic pH	ISO Inferred from Sequence Orthology more info
involved_in response to acidic pH	ISS Inferred from Sequence or Structural Similarity more info
involved_in response to ischemia	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to molecule of bacterial origin	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor

Names: 12-(S)-HETE receptor; G-protein coupled receptor 31

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.