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    Rtp2 receptor (chemosensory) transporter protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303835, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rtp2provided by RGD
    Official Full Name
    receptor (chemosensory) transporter protein 2provided by RGD
    Primary source
    RGD:1565722
    See related
    EnsemblRapid:ENSRNOG00000022160 AllianceGenome:RGD:1565722
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565722
    Summary
    Predicted to enable olfactory receptor binding activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste; protein insertion into membrane; and protein targeting to membrane. Predicted to be active in cell surface. Orthologous to human RTP2 (receptor transporter protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human mouse all
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    Genomic context

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    See Rtp2 in Genome Data Viewer
    Location:
    11q23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (90422553..90436684)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (76917904..76930760)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (80319177..80331599)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095689 Neighboring gene BCL6, transcription repressor Neighboring gene uncharacterized LOC134481024 Neighboring gene somatostatin Neighboring gene uncharacterized LOC134480929

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. RTP family members induce functional expression of mammalian odorant receptors. Saito H, et al. Cell, 2004 Nov 24. PMID 15550249
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables olfactory receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of bitter taste IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein insertion into membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein insertion into membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    receptor-transporting protein 2
    Names
    receptor transporter protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107083.2 → NP_001100553.1  receptor-transporting protein 2

      See identical proteins and their annotated locations for NP_001100553.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6JS11, D3ZCW1
      Related
      ENSRNOP00000036068.4, ENSRNOT00000036777.6
      Conserved Domains (1) summary
      pfam13695
      Location:51 → 161
      zf-3CxxC; Zinc-binding domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      90422553..90436684
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039088296.2 → XP_038944224.1  receptor-transporting protein 2 isoform X1

      Conserved Domains (1) summary
      pfam13695
      Location:51 → 161
      zf-3CxxC; Zinc-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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