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    RT1-CE13 RT1 class I, locus CE13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 414790, updated on 27-Nov-2024

    Summary

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    Official Symbol
    RT1-CE13provided by RGD
    Official Full Name
    RT1 class I, locus CE13provided by RGD
    Primary source
    RGD:1359196
    See related
    AllianceGenome:RGD:1359196
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Lung (RPKM 128.4), Spleen (RPKM 111.4) and 9 other tissues See more
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    Genomic context

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    See RT1-CE13 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (3314491..3322815, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (3314830..3318106, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 Unlocalized Scaffold NW_007906368.1 (3928..4540, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120098828 Neighboring gene Cdk2ap1-ps7 pseudogene Neighboring gene RT1 class I, locus CE12 Neighboring gene RT1 class I, locus CE14 Neighboring gene uncharacterized LOC120098829 Neighboring gene Cdk2ap1-ps6 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. [Association of HLA antigens with thyrotoxic periodic paralysis]. Liu WH, et al. Zhonghua Nei Ke Za Zhi, 1991 Jul. PMID 1752149
    2. Immune dysfunction and immune restoration disease in HIV patients given highly active antiretroviral therapy. Price P, et al. J Clin Virol, 2001 Oct. PMID 11564593
    3. Profiling of human leukocyte antigens in Eales' disease. Biswas J, et al. Int Ophthalmol, 1997-1998. PMID 9756436
    4. Human leukocyte antigen class I expression. Marker of poor prognosis in uveal melanoma. Blom DJ, et al. Invest Ophthalmol Vis Sci, 1997 Aug. PMID 9286277
    5. Synthetic MHC class I peptide prolongs cardiac survival and attenuates transplant arteriosclerosis in the Lewis-->Fischer 344 model of chronic allograft rejection. Murphy B, et al. Transplantation, 1997 Jul 15. PMID 9233694

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    RT1 class I, locus CE13
    Names
    RT1 class I, CE13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008836.2 → NP_001008836.1  RT1 class I, locus CE13 precursor

      See identical proteins and their annotated locations for NP_001008836.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000020
      UniProtKB/TrEMBL
      Q6MG31
      Conserved Domains (3) summary
      cd07698
      Location:207 → 299
      IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain
      pfam00129
      Location:25 → 203
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
      pfam06623
      Location:337 → 364
      MHC_I_C; MHC_I C-terminus

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      3314491..3322815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279406.1 → XP_063135476.1  RT1 class I, locus CE13 isoform X2

    2. XM_063279407.1 → XP_063135477.1  RT1 class I, locus CE13 isoform X3

    3. XM_063279408.1 → XP_063135478.1  RT1 class I, locus CE13 isoform X4

      UniProtKB/TrEMBL
      A0A2P1NRY3

    4. XM_063279405.1 → XP_063135475.1  RT1 class I, locus CE13 isoform X1

    RNA

    1. XR_010060748.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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