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    Abcg3l1 ATP-binding cassette, subfamily G (WHITE), member 3-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289453, updated on 27-Nov-2024

    Summary

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    Symbol
    Abcg3l1provided by RGD
    Full Name
    ATP-binding cassette, subfamily G (WHITE), member 3-like 1provided by RGD
    Primary source
    RGD:1303294
    See related
    EnsemblRapid:ENSRNOG00000069481 AllianceGenome:RGD:1303294
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Abcg3
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity; efflux transmembrane transporter activity; and riboflavin transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in gout; hematologic cancer (multiple); renal cell carcinoma; and toxic encephalopathy. Orthologous to human ABCG2 (ATP binding cassette subfamily G member 2 (JR blood group)). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 59.7), Adrenal (RPKM 59.5) and 9 other tissues See more
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    Genomic context

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    See Abcg3l1 in Genome Data Viewer
    Location:
    14p22
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (5429242..5481948, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (5124541..5177265, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (6488655..6541220, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 996 like 2 Neighboring gene zinc finger protein 951 like 1 Neighboring gene uncharacterized LOC134481818 Neighboring gene THO complex subunit 2-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC114213

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in riboflavin transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    broad substrate specificity ATP-binding cassette transporter ABCG2
    Names
    ATP-binding cassette, sub-family G (WHITE), member 3
    ATP-binding cassette, sub-family G (WHITE), member 3-like 1
    NP_001004076.2
    XP_017454584.1
    XP_017454585.1
    XP_038947589.1
    XP_063128962.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004076.2 → NP_001004076.2  broad substrate specificity ATP-binding cassette transporter ABCG2

      See identical proteins and their annotated locations for NP_001004076.2

      Status: PROVISIONAL

      Source sequence(s)
      BC098896
      UniProtKB/TrEMBL
      Q4KM08, Q68HW7
      Related
      ENSRNOP00000046549.3, ENSRNOT00000042532.8
      Conserved Domains (3) summary
      TIGR00955
      Location:64 → 644
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:369 → 572
      ABC2_membrane; ABC-2 type transporter
      cl21455
      Location:35 → 261
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      5429242..5481948 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017599095.3 → XP_017454584.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X1

      UniProtKB/TrEMBL
      Q4KM08, Q68HW7
      Conserved Domains (3) summary
      TIGR00955
      Location:64 → 644
      3a01204; The Eye Pigment Precursor Transporter (EPP) Family protein
      pfam01061
      Location:369 → 572
      ABC2_membrane; ABC-2 type transporter
      cl21455
      Location:35 → 261
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. XM_063272892.1 → XP_063128962.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X3

    3. XM_017599096.3 → XP_017454585.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X2

      UniProtKB/TrEMBL
      Q68HW7

    4. XM_039091661.2 → XP_038947589.1  broad substrate specificity ATP-binding cassette transporter ABCG2 isoform X4

      Conserved Domains (2) summary
      pfam19055
      Location:237 → 293
      ABC2_membrane_7; ABC-2 type transporter
      cl38936
      Location:35 → 261
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RNA

    1. XR_010057347.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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