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    Crip3 cysteine-rich protein 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 501100, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Crip3provided by RGD
    Official Full Name
    cysteine-rich protein 3provided by RGD
    Primary source
    RGD:1565018
    See related
    EnsemblRapid:ENSRNOG00000018613 AllianceGenome:RGD:1565018
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565018
    Summary
    Predicted to enable metal ion binding activity. Predicted to act upstream of or within T cell proliferation. Predicted to be located in cytoplasm. Orthologous to human CRIP3 (cysteine rich protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 2.1), Kidney (RPKM 1.5) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Crip3 in Genome Data Viewer
    Location:
    9q12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (22052039..22054933, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (14554450..14557344, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (16931862..16934714, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Neighboring gene tau tubulin kinase 1 Neighboring gene solute carrier family 22 member 7 Neighboring gene zinc finger protein 318 Neighboring gene small nucleolar RNA, H/ACA box 38 Neighboring gene uncharacterized LOC120094785

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification and characterization of thymus LIM protein: targeted disruption reduces thymus cellularity. Kirchner J, et al. Mol Cell Biol, 2001 Dec. PMID 11713292, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within T cell proliferation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    NOT located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    cysteine-rich protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109303.2 → NP_001102773.1  cysteine-rich protein 3

      See identical proteins and their annotated locations for NP_001102773.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/TrEMBL
      A6JIR0, A6JIR1, D3ZNQ0
      Related
      ENSRNOP00000058221.2, ENSRNOT00000061503.4
      Conserved Domains (2) summary
      cd09476
      Location:5 → 58
      LIM1_TLP; The first LIM domain of thymus LIM protein (TLP)
      cl02475
      Location:124 → 177
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      22052039..22054933 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039084062.1 → XP_038939990.1  cysteine-rich protein 3 isoform X1

      Conserved Domains (1) summary
      cd09477
      Location:74 → 127
      LIM2_TLP; The second LIM domain of thymus LIM protein (TLP)

    2. XM_039084063.1 → XP_038939991.1  cysteine-rich protein 3 isoform X1

      Conserved Domains (1) summary
      cd09477
      Location:74 → 127
      LIM2_TLP; The second LIM domain of thymus LIM protein (TLP)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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