Ssr3 signal sequence receptor, gamma [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ssr3provided by MGI
Official Full Name: signal sequence receptor, gammaprovided by MGI
Primary source: MGI:MGI:1914687
See related: Ensembl:ENSMUSG00000027828 AllianceGenome:MGI:1914687
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: TRAPG; 0610038P07Rik
Summary: Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in genitourinary system. Orthologous to human SSR3 (signal sequence receptor subunit 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in placenta adult (RPKM 100.6), limb E14.5 (RPKM 73.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 3 E1; 3 30.15 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (65287078..65299974, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (65379657..65392553, complement)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Results suggest that Trap-gamma appears to be required for vascular network formation in murine placental development.
Title: Translocon-associated protein subunit Trap-γ/Ssr3 is required for vascular network formation in the mouse placenta.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (1) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

AU022074 (e-PCR)
- UniSTS:207501

RH125395 (e-PCR)
- UniSTS:162217

AW553833 (e-PCR)
- UniSTS:185540

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in SRP-dependent cotranslational protein targeting to membrane	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: translocon-associated protein subunit gamma

Names: SSR-gamma; TRAP-gamma; signal sequence receptor subunit gamma; translocon-associated protein gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_026155.3 → NP_080431.1 translocon-associated protein subunit gamma

See identical proteins and their annotated locations for NP_080431.1

Status: PROVISIONAL

Source sequence(s)

AC113279

Consensus CDS

CCDS17386.1

UniProtKB/Swiss-Prot

Q8C0Z8, Q9DCF9

UniProtKB/TrEMBL

Q4FK79

Related

ENSMUSP00000029414.6, ENSMUST00000029414.12

Conserved Domains (1) summary

pfam07074
Location:12 → 183

TRAP-gamma; Translocon-associated protein, gamma subunit (TRAP-gamma)