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    ILF3-DT ILF3 divergent transcript [ Homo sapiens (human) ]

    Gene ID: 147727, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ILF3-DTprovided by HGNC
    Official Full Name
    ILF3 divergent transcriptprovided by HGNC
    Primary source
    HGNC:HGNC:27115
    See related
    Ensembl:ENSG00000267100 AllianceGenome:HGNC:27115
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ILF3-AS1
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    Genomic context

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    See ILF3-DT in Genome Data Viewer
    Location:
    19p13.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (10651862..10653872, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (10778349..10780357, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (10762538..10764548, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10084 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13981 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10085 Neighboring gene LSM2 pseudogene 1 Neighboring gene solute carrier family 44 member 2 (CTL2 blood group) Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:10734687-10735268 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:10747236-10747758 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:10763030-10763532 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:10763533-10764034 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13983 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10086 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10087 Neighboring gene interleukin enhancer binding factor 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:10801737-10802532 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:10802533-10803326 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:10806023-10806522 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10088 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:10811832-10812580 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13985 Neighboring gene queuine tRNA-ribosyltransferase catalytic subunit 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanism underlying long non‑coding RNA ILF3‑AS1‑mediated inhibition of cervical cancer cell proliferation, invasion and migration, and promotion of apoptosis. Zhu L, et al. Mol Med Rep, 2021 Aug. PMID 34080029, Free PMC Article
    2. Up-regulated long non-coding RNA ILF3-AS1 indicates poor prognosis of nasopharyngeal carcinoma and promoted cell metastasis. Yang X, et al. Int J Biol Markers, 2020 Dec. PMID 32962500
    3. LncRNA ILF3-AS1 mediated the occurrence of epilepsy through suppressing hippocampal miR-212 expression. Cai X, et al. Aging (Albany NY), 2020 May 13. PMID 32404536, Free PMC Article
    4. LncRNA ILF3-AS1 mediates oxidative stress and inflammation through miR-504-3p/HMGB1 axis in a cellular model of temporal lobe epilepsy. Gao P, et al. Brain Behav, 2024 Aug. PMID 39135276, Free PMC Article
    5. Long noncoding RNA ILF3-AS1 promotes cell proliferation, migration, and invasion via negatively regulating miR-200b/a/429 in melanoma. Chen X, et al. Biosci Rep, 2017 Dec 22. PMID 28935763, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LncRNA ILF3-AS1 mediates oxidative stress and inflammation through miR-504-3p/HMGB1 axis in a cellular model of temporal lobe epilepsy.
      Title: LncRNA ILF3-AS1 mediates oxidative stress and inflammation through miR-504-3p/HMGB1 axis in a cellular model of temporal lobe epilepsy.
    2. Mechanism underlying long noncoding RNA ILF3AS1mediated inhibition of cervical cancer cell proliferation, invasion and migration, and promotion of apoptosis.
      Title: Mechanism underlying long non‑coding RNA ILF3‑AS1‑mediated inhibition of cervical cancer cell proliferation, invasion and migration, and promotion of apoptosis.
    3. Up-regulated long non-coding RNA ILF3-AS1 indicates poor prognosis of nasopharyngeal carcinoma and promoted cell metastasis.
      Title: Up-regulated long non-coding RNA ILF3-AS1 indicates poor prognosis of nasopharyngeal carcinoma and promoted cell metastasis.
    4. LncRNA ILF3-AS1 mediated the occurrence of epilepsy through suppressing hippocampal miR-212 expression.
      Title: LncRNA ILF3-AS1 mediated the occurrence of epilepsy through suppressing hippocampal miR-212 expression.
    5. The expression levels of lncRNA ILF3-AS1 was up-regulated in osteosarcoma tissues and cell lines, and was modulated by SP1. LncRNA ILF3-AS1 promoted osteosarcoma cells proliferation and metastasis via modulation of miR-212-SOX5 pathway.
      Title: SP1-mediated upregulation of lncRNA ILF3-AS1 functions a ceRNA for miR-212 to contribute to osteosarcoma progression via modulation of SOX5.
    6. Long noncoding RNA ILF3-AS1 promotes EZH2-mediated cell proliferation, migration, and invasion via negatively regulating miR-200b/a/429 in melanoma.
      Title: Long noncoding RNA ILF3-AS1 promotes cell proliferation, migration, and invasion via negatively regulating miR-200b/a/429 in melanoma.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Markers

    Other Names

    • CTC-539A10.4
    • ILF3 antisense RNA 1 (head to head)
    • ILF3 antisense RNA 1 (non-protein coding)
    • ILF3 divergent tranacript

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_024333.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL832185, BC007593, BC044911, DB002247
      Related
      ENST00000591501.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      10651862..10653872 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      10778349..10780357 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_203300.1: Suppressed sequence

      Description
      NM_203300.1: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.