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    SIP4 Sip4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853356, updated on 27-Dec-2024

    Summary

    Official Symbol
    SIP4
    Official Full Name
    Sip4p
    Primary source
    SGD:S000003625
    Locus tag
    YJL089W
    See related
    AllianceGenome:SGD:S000003625; FungiDB:YJL089W; VEuPathDB:YJL089W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of invasive growth in response to glucose limitation; positive regulation of gluconeogenesis; and positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See SIP4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (265926..268415)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene glucosaminyl-phosphotidylinositol O-acyltransferase Neighboring gene protein kinase activating protein DPB11 Neighboring gene ornithine carbamoyltransferase Neighboring gene tRNA ligase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Sip4p
    NP_012446.1
    • C6 zinc cluster transcriptional activator; binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      265926..268415
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181522.1NP_012446.1  TPA: Sip4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012446.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VW95, P46954
      UniProtKB/TrEMBL
      C7GR25, N1P0T7
      Conserved Domains (2) summary
      smart00066
      Location:4082
      GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
      cd15486
      Location:85102
      ZIP_Sip4; Leucine zipper Dimerization domain transcription factor Sip4p and similar fungal proteins