U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Hcfc1r1 host cell factor C1 regulator 1 (XPO1-dependent) [ Mus musculus (house mouse) ]

    Gene ID: 353502, updated on 27-Nov-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Hcfc1r1provided by MGI
    Official Full Name
    host cell factor C1 regulator 1 (XPO1-dependent)provided by MGI
    Primary source
    MGI:MGI:2663619
    See related
    Ensembl:ENSMUSG00000023904 AllianceGenome:MGI:2663619
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HPIP
    Summary
    Predicted to be located in nucleoplasm. Is expressed in cranial ganglion; dorsal root ganglion; medulla oblongata lateral wall; olfactory epithelium; and ventral grey horn. Orthologous to human HCFC1R1 (host cell factor C1 regulator 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in stomach adult (RPKM 169.5), adrenal adult (RPKM 159.4) and 25 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Hcfc1r1 in Genome Data Viewer
    Location:
    17 A3.3; 17 11.98 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (23892570..23894499)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (23673608..23675524)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 25 Neighboring gene ribosomal protein L36 pseudogene Neighboring gene BICD family like cargo adaptor 2 Neighboring gene STARR-positive B cell enhancer ABC_E8656 Neighboring gene THO complex 6 Neighboring gene tumor necrosis factor receptor superfamily, member 12a Neighboring gene claudin 6 Neighboring gene claudin 9

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Interaction of HCF-1 with a cellular nuclear export factor. Mahajan SS, et al. J Biol Chem, 2002 Nov 15. PMID 12235138, Free PMC Article
    2. Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Zhang X, et al. Commun Biol, 2024 Mar 23. PMID 38521877, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    host cell factor C1 regulator 1
    Names
    HCF-1 beta-propeller-interacting protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001414380.1 → NP_001401309.1  host cell factor C1 regulator 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154766
      UniProtKB/Swiss-Prot
      Q9CYQ5
      Related
      ENSMUSP00000137336.2, ENSMUST00000180140.8

    2. NM_001414381.1 → NP_001401310.1  host cell factor C1 regulator 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC154766
      UniProtKB/Swiss-Prot
      Q9CYQ5

    3. NM_001414382.1 → NP_001401311.1  host cell factor C1 regulator 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC154766

    4. NM_001414383.1 → NP_001401312.1  host cell factor C1 regulator 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154766
      UniProtKB/TrEMBL
      J3QPD4
      Related
      ENSMUSP00000137205.2, ENSMUST00000179928.2

    5. NM_001414384.1 → NP_001401313.1  host cell factor C1 regulator 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154766
      UniProtKB/TrEMBL
      J3QPD4

    6. NM_001414385.1 → NP_001401314.1  host cell factor C1 regulator 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC154766

    7. NM_001414386.1 → NP_001401315.1  host cell factor C1 regulator 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC154766
      UniProtKB/TrEMBL
      J3QPD4

    8. NM_001414387.1 → NP_001401316.1  host cell factor C1 regulator 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC154766

    9. NM_001414470.1 → NP_001401399.1  host cell factor C1 regulator 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC154766

    10. NM_181821.3 → NP_861542.1  host cell factor C1 regulator 1 isoform 1

      See identical proteins and their annotated locations for NP_861542.1

      Status: VALIDATED

      Source sequence(s)
      AC154766
      Consensus CDS
      CCDS28455.1
      UniProtKB/Swiss-Prot
      Q9CYQ5
      Related
      ENSMUSP00000024697.5, ENSMUST00000024697.5
      Conserved Domains (1) summary
      pfam15226
      Location:2 → 116
      HPIP; HCF-1 beta-propeller-interacting protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      23892570..23894499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CYQ5.1 GenPept UniProtKB/Swiss-Prot:Q9CYQ5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools