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    Rimbp3 RIMS binding protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 239731, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rimbp3provided by MGI
    Official Full Name
    RIMS binding protein 3provided by MGI
    Primary source
    MGI:MGI:2685449
    See related
    Ensembl:ENSMUSG00000071636 AllianceGenome:MGI:2685449
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm603; Gm1759; RIM-BP3; mKIAA1666
    Summary
    Predicted to enable benzodiazepine receptor binding activity. Involved in fertilization and spermatid development. Located in nucleus. Colocalizes with manchette. Orthologous to human RIMBP3 (RIMS binding protein 3); RIMBP3B (RIMS binding protein 3B); and RIMBP3C (RIMS binding protein 3C). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Rimbp3 in Genome Data Viewer
    Location:
    16 A3; 16 10.67 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (17025999..17031846)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (17208135..17213982)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2L 3 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:17201546-17201655 Neighboring gene predicted gene, 22129 Neighboring gene STARR-seq mESC enhancer starr_40246 Neighboring gene STARR-positive B cell enhancer ABC_E7430 Neighboring gene hypermethylated in cancer 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:17276268-17276485 Neighboring gene transmembrane protein 191

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables benzodiazepine receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in fertilization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in fertilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT involved_in neuromuscular synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spermatid development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with manchette IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    colocalizes_with manchette IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033338.3NP_001028510.2  RIMS-binding protein 3

      Status: VALIDATED

      Source sequence(s)
      AA030140, AC154667, AK133200, BG075083
      Consensus CDS
      CCDS27998.2
      UniProtKB/Swiss-Prot
      B9EJ89, E9PZY2, Q3V0F0, Q5DTW0
      Related
      ENSMUSP00000127909.2, ENSMUST00000169803.5
      Conserved Domains (3) summary
      smart00060
      Location:9821043
      FN3; Fibronectin type 3 domain
      TIGR02168
      Location:29671
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cl17036
      Location:826886
      SH3; Src Homology 3 domain superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      17025999..17031846
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)