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    Snap29 synaptosomal-associated protein 29 [ Mus musculus (house mouse) ]

    Gene ID: 67474, updated on 9-Dec-2024

    Summary

    Official Symbol
    Snap29provided by MGI
    Official Full Name
    synaptosomal-associated protein 29provided by MGI
    Primary source
    MGI:MGI:1914724
    See related
    Ensembl:ENSMUSG00000022765 AllianceGenome:MGI:1914724
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gs32; 1300018G05Rik
    Summary
    Predicted to enable SNAP receptor activity and syntaxin binding activity. Predicted to be involved in several processes, including autophagosome maturation; regulation of vesicle-mediated transport; and synaptic vesicle exocytosis. Located in autophagosome. Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; and sensory organ. Used to study CEDNIK syndrome. Human ortholog(s) of this gene implicated in CEDNIK syndrome. Orthologous to human SNAP29 (synaptosome associated protein 29). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 6.2), CNS E18 (RPKM 4.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Snap29 in Genome Data Viewer
    Location:
    16 A3; 16 10.79 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (17223864..17248690)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (17406000..17430826)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene serine (or cysteine) peptidase inhibitor, clade D, member 1 Neighboring gene STARR-seq mESC enhancer starr_40252 Neighboring gene predicted gene, 24927 Neighboring gene poly(A) binding protein, cytoplasmic 1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E4158 Neighboring gene v-crk avian sarcoma virus CT10 oncogene homolog-like Neighboring gene STARR-seq mESC enhancer starr_40255 Neighboring gene apoptosis-inducing factor, mitochondrion-associated 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (4)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables syntaxin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables syntaxin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in autophagosome maturation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in autophagosome maturation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in autophagosome membrane docking IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of synaptic vesicle cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of synaptic vesicle exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptic vesicle fusion to presynaptic active zone membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in synaptic vesicle priming IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SNARE complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SNARE complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in autophagosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in autophagosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ciliary pocket membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ciliary pocket membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in extrinsic component of synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    synaptosomal-associated protein 29
    Names
    SNAP-29
    golgi SNARE of 32 kDa
    soluble 29 kDa NSF attachment protein
    vesicle-membrane fusion protein SNAP-29

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023348.4NP_075837.3  synaptosomal-associated protein 29

      See identical proteins and their annotated locations for NP_075837.3

      Status: VALIDATED

      Source sequence(s)
      AC110573, AK005042, AK007065, AK039203, BB763685
      Consensus CDS
      CCDS28001.1
      UniProtKB/Swiss-Prot
      Q3UGN0, Q9DBC5, Q9ERB0
      Related
      ENSMUSP00000023449.9, ENSMUST00000023449.11
      Conserved Domains (2) summary
      cd15856
      Location:201259
      SNARE_SNAP29C; C-terminal SNARE motif of SNAP29
      cd15887
      Location:47111
      SNARE_SNAP29N; N-terminal SNARE motif of SNAP29

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      17223864..17248690
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)