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    Prr18 proline rich 18 [ Mus musculus (house mouse) ]

    Gene ID: 320111, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Prr18provided by MGI
    Official Full Name
    proline rich 18provided by MGI
    Primary source
    MGI:MGI:2443403
    See related
    Ensembl:ENSMUSG00000055945 AllianceGenome:MGI:2443403
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630019K15Rik
    Summary
    Is expressed in trachea epithelium. Orthologous to human PRR18 (proline rich 18). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 16.8), cortex adult (RPKM 8.8) and 6 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Prr18 in Genome Data Viewer
    Location:
    17 A1; 17 4.92 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (8546378..8562945)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (8340406..8344113)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1188 Neighboring gene RIKEN cDNA 4930506C21 gene Neighboring gene mitochondrial pyruvate carrier 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:8503785-8503968 Neighboring gene SFT2 domain containing 1 Neighboring gene predicted gene, 46592 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:8564858-8564967 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:8565311-8565494 Neighboring gene STARR-positive B cell enhancer ABC_E4191 Neighboring gene protein FAM32A pseudogene Neighboring gene brachyury 2 Neighboring gene predicted gene, 16702 Neighboring gene ribosomal protein L15 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Chloride channels regulate differentiation and barrier functions of the mammalian airway. He M, et al. Elife, 2020 Apr 14. PMID 32286221, Free PMC Article
    2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    proline-rich protein 18
    Names
    proline rich region 18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399587.1 → NP_001386516.1  proline-rich protein 18 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC164431
      UniProtKB/Swiss-Prot
      Q6PAN7, Q8BR84, Q8CA32, Q8CBI5
      Related
      ENSMUSP00000069019.7, ENSMUST00000069742.8

    2. NM_178774.4 → NP_848889.3  proline-rich protein 18 isoform 1

      See identical proteins and their annotated locations for NP_848889.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript but encodes the functional protein.
      Source sequence(s)
      AC164431, AK045379, BC060190
      Consensus CDS
      CCDS28382.1
      UniProtKB/Swiss-Prot
      Q6PAN7, Q8BR84, Q8CA32, Q8CBI5
      Related
      ENSMUSP00000127393.2, ENSMUST00000163887.2
      Conserved Domains (1) summary
      pfam15671
      Location:55 → 307
      PRR18; Proline-rich protein family 18

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      8546378..8562945
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160645.1 → XP_036016538.1  proline-rich protein 18 isoform X1

      UniProtKB/Swiss-Prot
      Q6PAN7, Q8BR84, Q8CA32, Q8CBI5
      Conserved Domains (1) summary
      pfam15671
      Location:55 → 307
      PRR18; Proline-rich protein family 18

    2. XM_036160644.1 → XP_036016537.1  proline-rich protein 18 isoform X1

      UniProtKB/Swiss-Prot
      Q6PAN7, Q8BR84, Q8CA32, Q8CBI5
      Conserved Domains (1) summary
      pfam15671
      Location:55 → 307
      PRR18; Proline-rich protein family 18
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PAN7.2 GenPept UniProtKB/Swiss-Prot:Q6PAN7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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